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OpenSampling

The Library

Papers on microsampling and monitoring, each with a finding paraphrased to our standard and labelled in one vocabulary. With a free account, every entry links to a legitimate copy; nothing is copied from an abstract.

Papers 1–5 of 256 labelled “Haematocrit”, newest first.

  1. 2026

    Clinical Validation of Venetoclax Volumetric Microsampling in Leukemia, with Whole-Blood-to-Plasma Conversion and Self-Microsampling Feasibility

    In AML and CLL, 91% of VAMS venetoclax results fell within 20% of plasma after individualised haematocrit correction; in home sampling,

    Levens et al., Clinical Pharmacokinetics (paywalled)

  2. 2026

    Evaluation of hematocrit-adjusted conversion strategies for mycophenolic acid and tacrolimus monitoring using volumetric absorptive microsampling in lung and renal transplant recipients

    In lung and renal transplant recipients, VAMS sampling with LC-MS/MS quantification of mycophenolic acid and tacrolimus showed good linearity and accuracy, and with a haematocrit-adjusted conversion formula achieved clinical agreement in most samples; tacrolimus did not require haematocrit correction.

    Juan et al., Journal of pharmacy & pharmaceutical sciences

  3. 2026

    A Review of Blood-Based Microsampling Devices for Patient-Centered Application in Therapeutic Drug Monitoring

    This review found that volumetric microsampling devices, such as Mitra, HemaPEN, HemaXis DB10, and Tasso-M20, overcome haematocrit bias, whilst Telimmune plasma separation cards enable direct plasma collection without centrifugation.

    Huhn & Scherf-Clavel, Therapeutic drug monitoring (paywalled)

  4. 2026

    Analytical validation of a dried blood microsampling method to measure androstenedione, 17α‑hydroxyprogesterone, and 11‑ketotestosterone for congenital adrenal hyperplasia monitoring

    A liquid chromatography-tandem mass spectrometry method was successfully validated for measuring androstenedione, 17α-hydroxyprogesterone, and 11-ketotestosterone in dried blood samples collected via volumetric absorptive microsampling.

    De Baets et al., Talanta (paywalled)

  5. 2026

    Clinical validation of a DBS-based LC-MS/MS method for 25-hydroxyvitamin D: from lab sampling to home sampling

    Capillary dried blood spots, after haematocrit-dependent conversion, showed good agreement with plasma for 25-hydroxyvitamin D quantification,

    Heughebaert et al., Clinical chemistry and laboratory medicine (paywalled)

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