The Library
1530 papers on microsampling and monitoring, each with a finding paraphrased to our standard and labelled in one vocabulary. Every entry links to a legitimate copy; nothing is copied from an abstract.
52 papers labelled “genotyping”, newest first.
2026
DNA methylation markers in first-void urine effectively detect high-grade cervical lesions in HPV-positive women, with results similar to clinician-collected samples in those over 30. This enables reliable cervical cancer screening using self-collected urine, reducing the need for invasive follow-up procedures in decentralised settings.
Evaluating DNA methylation markers and extended HPV genotyping in first-void urine for detecting high-grade cervical lesions in HPV-positive women: a cross-sectional study — Tranberg et al., BMC medicine
- colli-pee
- first-void
- self-collection
- hpv
- urine
- biomarkers
- genotyping
2026
A comparison of human papillomavirus detection in first-void urine and cervicovaginal samples from Colombian women showed moderate prevalence but weak concordance between the two methods. Although urine-based screening offers a non-invasive alternative, its limited diagnostic performance in this study highlights the ongoing need to optimise collection and processing strategies for decentralised screening.
HPV detection in first void urine and cervicovaginal samples: comparative study and analysis of associated factors in women from tunja, colombia — Neita et al., Preventive medicine reports
- first-void
- sti
- hpv
- urine
- genotyping
2026
Dried urine strips demonstrated high diagnostic accuracy and stability for chlamydia and gonorrhea detection compared to standard urine samples. This method supports decentralised screening by allowing self-collection and ambient temperature transport without compromising sample integrity.
Development and evaluation of dried urine strip for genital chlamydia and gonorrhea testing — Gibbons et al., Journal of clinical microbiology
- sti
- self-collection
- dried
- urine
- validation
- genotyping
2026
Dried blood spot collection proved feasible during parabolic flight, with seventeen of twenty volunteers successfully providing samples for caffeine pharmacokinetic profiling. The method yielded stable metabolic ratios between ground and weightless conditions, and participants reported high satisfaction, suggesting DBS could support therapeutic drug monitoring in remote or extreme environments such as long-term spaceflight.
Feasibility of dried blood spot collection for caffeine pharmacokinetic studies in microgravity: Insights from parabolic flight campaigns — Derobertmasure et al., British journal of clinical pharmacology
- blood
- dried
- dbs
- self-collection
- acceptability
- tdm
- genotyping
2026
This study demonstrated that a fully remote genome sequencing study using self-collected dried blood spots and buccal swabs is feasible for individuals with Prader-Willi syndrome, with all participants completing the study and reporting the process was easy despite being lengthy. The design successfully returned actionable genetic findings, including those related to blood clot formation, to participants.
Study design with responsible return of results for a fully remote genome sequencing study in individuals with Prader-Willi syndrome — Vrana-Diaz et al., Genetics in medicine open
- blood
- saliva
- dried
- dbs
- self-collection
- acceptability
- dct
- genotyping
2025
A study of 100 Brazilian women with high-grade cervical lesions found excellent concordance for high-risk HPV detection between clinician-collected samples and patient-centric, self-collected vaginal or first-void urine samples. Self-sampling was preferred for comfort, though the study's single-centre setting may limit generalisability.
Self-sampling for HPV genotyping: a study of vaginal and urine collection in Brazilian women with high-grade lesions — Castanheira et al., Clinics
- acceptability
- first-void
- sti
- self-collection
- hpv
- urine
- genotyping
2025
The study validated the Allplex HPV28 assay for use with first-void urine samples collected using a Colli-Pee device, finding good agreement with a reference method and that it works without pre-centrifugation. This provides a reliable, non-invasive option for HPV screening and vaccine monitoring, which is important for increasing participation in decentralised settings.
Optimization and analytical validation of the Allplex HPV28 genotyping assay for use in first-void urine samples — Bell et al., Journal of clinical microbiology
- colli-pee
- first-void
- sti
- hpv
- urine
- validation
- genotyping
2025
This study found that a decontamination pipeline using metagenome-assembled genomes improves the accuracy of variant calling from saliva samples, showing superior concordance with blood-derived results compared to conventional methods. These results validate the potential of self-collected oral samples for accurate personal genotyping.
Metagenome-assembled genomes enhance bacterial read decontamination and variant calling in oral samples — An et al., iScience
- venous-agreement
- blood
- microbiome
- validation
- saliva
- genotyping
2025
The hrHPV ReadyMix qPCR Kit detected high-risk HPV DNA in self-collected urine with 80.9% sensitivity and 100% specificity when compared to cervical swabs. Urine testing identified a similar HPV prevalence (6.28%) to cervical swabs (6.62%), suggesting this non-invasive method could expand cervical cancer screening programmes in low-resource settings.
Urinary detection of high-risk HPV DNA to enhance cervical cancer screening in developing countries — Intan et al., Microbiology spectrum
- urine
- self-collection
- validation
- genotyping
- hpv
- sti
2025
Whole-genome sequencing of dried blood spots from 1,000 newborns identified 16 infants with high-chance results, most missed by standard screening. The 13-day turnaround and high parental acceptability show a feasible, scalable model for decentralised genomic screening.
Feasibility, acceptability and clinical outcomes of the BabyScreen+ genomic newborn screening study — Lunke et al., Nature medicine
- blood
- dried
- dbs
- acceptability
- pediatric
- genotyping
2024
Self-collected oral sponge sampling found high accuracy for HPV DNA detection in oral cancer patients, with 100% specificity, 85.7% sensitivity and an AUC of 0.93, compared to oral rinse. The authors note larger cohorts are required to confirm performance.
Human Papilloma Virus (HPV) Detection in Oral Rinse vs. Oral Sponge: A Preliminary Accuracy Report in Oral Cancer Patients — Panzarella et al., Cancers
- self-collection
- hpv
- liquid
- saliva
- genotyping
2024
Using the Oragene saliva device, this study identified elevated CYP2C8 allele frequencies in a Saudi paediatric cohort compared to other Asian populations, suggesting potential variability in ibuprofen metabolism and drug response.
Pediatric pharmacogenetics: profiling CYP2C8 polymorphisms at King Abdulaziz University Dental Clinic — Bagher et al., Drug metabolism and personalized therapy (paywalled)
- saliva
- dna-genotek-oragene
- pediatric
- genotyping
2024
In pregnant women, first-void urine collected at midgestation detected HPV in 38%, with high-risk genotypes and high viral loads associated with placental HPV infection at delivery (prevalence 3%). No increased risk of adverse pregnancy outcomes was observed with placental HPV. This demonstrates urine-based HPV screening can identify placental infection risk non-invasively.
Placental human papillomavirus infections and adverse pregnancy outcomes — Værnesbranden et al., Placenta (paywalled)
- urine
- first-void
- genotyping
- hpv
2024
Self-collected urine samples detected high-risk HPV DNA in 25.5 per cent of women and 8 per cent of men by qPCR, while oral gargle samples detected HPV in 7 per cent of women and 5 per cent of men. With good diagnostic accuracy against Pap smear, qPCR on self-collected specimens offers a viable decentralised approach to HPV screening in remote populations.
Evaluating different samples & techniques for hr-HPV DNA genotyping to improve the efficiency of risk profiling for oral & cervical cancers in Sikkim, India — Gupta et al., The Indian journal of medical research
- saliva
- urine
- self-collection
- validation
- genotyping
- hpv
- sti
2023
Using the Oragene Discovery 500 series for decentralised saliva collection in 524 African American adolescents, this study found that positive neighbourhood conditions relate to fewer behavioural difficulties, despite genetic risk. The authors note that most gene-environment studies of behaviour use European ancestry samples, limiting generalisability to African American youth.
Genetic Risk, Neighborhood Characteristics, and Behavioral Difficulties Among African American Adolescents Living in Very Low-Income Neighborhoods — Sterrett-Hong et al., Research on child and adolescent psychopathology (paywalled)
- dna-genotek-oragene
- pediatric
- saliva
- genotyping
2023
Using patient-centric saliva microsampling with the Oragene kit, the study found a low overall prevalence, 13%, of the OPRM1 118G allele in a Western Saudi population, with a significantly higher frequency in females, 21%, than males, 5%. The authors note the findings are specific to this population and may not be generalisable.
Allele frequency and genotype distribution of the opioid receptor μ-1 (OPRM1) A118G polymorphism in the Western Saudi population — Bagher & Hareeri, Journal of applied biomedicine (paywalled)
- saliva
- dna-genotek-oragene
- genotyping
2023
The study found that the Oragene OG-600 receptacle provided the highest concentration of salivary DNA, including short fragments suitable for analysis, and successfully detected HPV DNA from patient saliva. This matters for decentralised sampling as it supports the use of a standardised, self-collection device for non-invasive cancer biomarker detection.
Isolation of salivary cell-free DNA for cancer detection — Brooks et al., PloS one
- dna-genotek-oragene
- hpv
- liquid-biopsy
- liquid
- saliva
- genotyping
2023
This study of 184 individuals showed that home collection of dried blood spots and saliva can identify genetic polymorphisms linked to cardiac serum markers. Seven SNPs associated significantly with markers such as Apo B, LDL Direct, and hsCRP, while a polygenic risk score correlated strongly with NT-proBNP (r²=0.82, P=.03) and ox-LDL (r²=0.94, P=.005). These results indicate decentralised genetic sampling could enable early cardiovascular risk assessment and identify patients requiring closer serological monitoring.
Influence of genetic polymorphisms on serum biomarkers of cardiac health — Krishnamurthy et al., Medicine
- blood
- saliva
- dried
- dbs
- self-collection
- genotyping
- biomarkers
2023
First-void urine identified merely 15.8% of HPV types in circumcised men with genital warts, the lowest detection rate of six sampling methods. Combining wart biopsy with swabs from four genital anatomical sites achieved 98.9% detection, demonstrating that multi-site collection is necessary for accurate decentralised HPV screening in this population.
Evaluation of the optimal sampling approach for HPV genotyping in circumcised heterosexual men with genital warts — Sarier et al., Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (paywalled)
- urine
- first-void
- genotyping
- hpv
- sti
2022
The AFFECT study successfully recruited and characterised 48,467 participants with major depression, bipolar disorder, and controls through a fully remote design. This demonstrates the viability of large-scale virtual and decentralised cohorts for deep phenotyping and genomic analysis of psychiatric conditions.
Characterizing mood disorders in the AFFECT study: a large, longitudinal, and phenotypically rich genetic cohort in the US — Dalby et al., Translational psychiatry
- dct
- genotyping
2020
A Danish virtual feasibility study of 55 adults with atopic dermatitis found that remote recruitment and self-collection of DNA samples by mail, combined with weekly smartphone tasks, achieved 96% retention and over 90% task adherence, over a short eight-week study with self-reported outcomes.
High adherence and low dropout rate in a virtual clinical study of atopic dermatitis through weekly reward-based personalized genetic lifestyle reports — Ali et al., PLOS ONE
- dct
- acceptability
- self-collection
- genotyping
2020
Self-collected saliva samples provided adequate DNA for genotyping in preterm birth research, though questionnaire data on birth details had limited concordance with prospective records, indicating that while DNA sampling is feasible via post, phenotyping requires more reliable data collection methods for genetic studies.
Postal recruitment for genetic studies of preterm birth: A feasibility study — Keag et al., Wellcome open research
- dct
- dna-genotek-oragene
- self-collection
- liquid
- saliva
- genotyping
2020
Testing 130 healthy adults, researchers found that a caffeine breath test can identify the rs4410790 genotype using saliva collected via the Oragene DNA saliva collection kit. However, breath metrics did not differ for rs762551 or rs5751876 genotypes, and all subjects had the CC genotype at rs2472297.
<sup>13</sup>C-caffeine breath test identifies single nucleotide polymorphisms associated with caffeine metabolism — Ishii et al., Drug metabolism and pharmacokinetics (paywalled)
- saliva
- dna-genotek-oragene
- genotyping
2020
Using OraGene kits for saliva collection from 210 Portuguese mothers, this study found that the 5-HTTLPR polymorphism moderates environmental effects on maternal sensitivity. While generalisability may be limited by the Portuguese community sample, the work shows that decentralised saliva sampling is viable for gene-environment interaction studies.
Does 5-HTTLPR moderate the effect of the quality of environmental context on maternal sensitivity? Testing the differential susceptibility hypothesis — Baião et al., Psychiatric genetics (paywalled)
- saliva
- dna-genotek-oragene
- genotyping
2020
Using the Oragene DNA self-collection kit, this study found no significant difference in CNTFR genotype frequencies between weightlifters, 56% CC, 32% CT and 12% TT, and controls, 53% CC, 40% CT and 7% TT. However, the CT+TT genotype was associated with higher relative performance, though the cross-sectional design limits causal inference.
Ciliary Neurotrophic Factor Receptor rs41274853 Polymorphism Is Associated With Weightlifting Performance in Japanese Weightlifters — Homma et al., Journal of strength and conditioning research (paywalled)
- saliva
- dna-genotek-oragene
- self-collection
- genotyping
2020
Using a patient-centric saliva microsampling kit, the study found that genetic variants, VKORC1 and CYP2C9, and smoking explained 39.2% of warfarin dose variability in a Qatari population, supporting decentralised sampling for pharmacogenomic profiling.
The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population — Bader et al., The pharmacogenomics journal (paywalled)
- tdm
- dna-genotek-oragene
- self-collection
- saliva
- genotyping
2020
This proof-of-principle study found that baseline salivary DNA methylation, collected using the Oragene DNA kit, predicted childhood obesity three years later. A child at the 75th percentile of NRF1 methylation had a 48% chance of obesity versus 30% at the 25th percentile, showing the value of salivary microsampling for paediatric screening.
Salivary epigenetic biomarkers as predictors of emerging childhood obesity — Rushing et al., BMC medical genetics
- saliva
- dna-genotek-oragene
- pediatric
- genotyping
2020
A targeted NGS panel using dried blood spots achieved 100% concordance with Sanger sequencing in detecting pathogenic variants across 32 samples, with average coverage of 596X. This validates microsampling for decentralised newborn screening programmes, enabling accurate genetic diagnosis from minimally invasive specimens.
A targeted gene capture next-generation sequencing panel for genetic screening of newborns — Peng et al., JPMA. The Journal of the Pakistan Medical Association (paywalled)
- blood
- dried
- dbs
- validation
- pediatric
- genotyping
2020
During urban reactive case detection for malaria in Lusaka, dried blood spot sampling was deployed for parasite genetic analysis alongside rapid diagnostic tests. However, high infection complexity and small sample numbers constrained the ability to discern transmission pathways from the genetic data.
The use of spatial and genetic tools to assess Plasmodium falciparum transmission in Lusaka, Zambia between 2011 and 2015 — Bridges et al., Malaria journal
- blood
- dried
- dbs
- serology
- genotyping
2019
Comparing matched samples from four individuals, this study found that blood-derived DNA yielded a higher percentage of aligned reads and mean read depth than saliva or buccal samples, p<0.05. While limited by a small sample size, these results suggest decentralised saliva or buccal sampling may be less reliable for whole-genome sequencing.
Impact of DNA source on genetic variant detection from human whole-genome sequencing data — Trost et al., Journal of medical genetics
- blood
- saliva
- genotyping
2019
Saliva self-collection at home and during clinical procedures yielded cortisol data from 326 children, revealing genetic variants in stress-response pathways that may identify paediatric patients at risk of adverse reactions to painful procedures, supporting tailored interventions in decentralised settings.
Genetic Variants and the Cortisol Response in Children: An Exploratory Study — Ersig et al., Biological research for nursing (paywalled)
- saliva
- self-collection
- pediatric
- cortisol
- genotyping
2018
Telomere length measurements vary significantly depending on the sample type used, with Oragene saliva showing a moderate correlation to venous buffy coat, whereas Oasis saliva and dried blood spots did not yield comparable or adequate results for this assay.
Evaluating minimally invasive sample collection methods for telomere length measurement — Goldman et al., American journal of human biology : the official journal of the Human Biology Council (paywalled)
- blood
- saliva
- dried
- dbs
- dna-genotek-oragene
- validation
- venous-agreement
- genotyping
2018
Both blood and saliva collection methods produced sufficient DNA for genotyping, with saliva using Oragene kits being less invasive and more acceptable for participants who declined blood draws, supporting its use in decentralised research settings
The MOSAICC study: Assessing feasibility for biological sample collection in epidemiology studies and comparison of DNA yields from saliva and whole blood samples — James et al., Annals of human genetics (paywalled)
- blood
- saliva
- dna-genotek-oragene
- acceptability
- genotyping
2018
A study of 307 youth aged 10 to 14 years found that DNA extracted from saliva collected with Oragene kits was suitable for genotyping the OXTR rs53576 variant. This supports decentralised paediatric genetic testing, although the study was limited by its reliance on a community sample.
Depression in early adolescence: Contributions from relational aggression and variation in the oxytocin receptor gene — Kushner et al., Aggressive behavior (paywalled)
- dna-genotek-oragene
- pediatric
- saliva
- genotyping
2018
Urine self-collection detected CIN2/3 with 90.2% sensitivity compared with 93.4% for cervical samples, showing moderate concordance (kappa 0.42) and similar HPV16 detection rates. This validates urine-based HPV screening as a less invasive, patient-centric approach that could expand cervical cancer screening coverage in decentralised healthcare settings.
Detection and genotyping of human papillomavirus virus (HPV): a comparative analysis of clinical performance in cervical and urine samples in Chilean women — Buchegger et al., International journal of clinical and experimental pathology (paywalled)
- urine
- self-collection
- genotyping
- hpv
- sti
2018
Singaporean women aged 40-69 showed significant preferences for sample type, pretest discussion provider, and out-of-pocket cost when considering SNP gene testing for breast cancer screening. Tailoring genetic testing to patient preferences may improve uptake, highlighting that acceptability of self-collected buccal swab and dried blood spot samples is crucial for decentralised screening programmes.
Women's preferences, willingness-to-pay, and predicted uptake for single-nucleotide polymorphism gene testing to guide personalized breast cancer screening strategies: a discrete choice experiment — Wong et al., Patient preference and adherence
- dbs
- self-collection
- acceptability
- genotyping
2017
Across five extraction protocols, storage time generally reduced DNA quantity but protocol 1 (Oragene) maintained yield; DNA purity was largely unaffected by storage for commercial protocols but declined for non‑commercial methods; only protocol 1 consistently gave unfragmented DNA and protocols 1–4 yielded amplifiable DNA while protocol 5 rarely did. This supports reliable saliva self‑collection and long‑term storage for genotyping in decentralised settings.
Human DNA extraction from whole saliva that was fresh or stored for 3, 6 or 12 months using five different protocols — Garbieri et al., Journal of applied oral science : revista FOB
- saliva
- dna-genotek-oragene
- validation
- genotyping
2017
Real-time mCOP-PCR on fresh blood DNA gave identical SMN1 deletion genotypes to PCR-RFLP and reduced turnaround from over 12 hours to four hours, offering a faster first-tier diagnostic method for SMA.
SMA Diagnosis: Detection of SMN1 Deletion with Real-Time mCOP-PCR System Using Fresh Blood DNA — Niba et al., The Kobe journal of medical sciences (paywalled)
- blood
- liquid
- genotyping
2017
Saliva self-collection with Oragene tubes enabled genotyping of COMT polymorphisms in children, revealing that the AA genotype buffers the negative effect of authoritarian parenting on long-term executive dysfunction after early childhood traumatic brain injury. This demonstrates how decentralised genetic sampling can support longitudinal neurodevelopmental studies in paediatric populations.
Catechol-O-Methyltransferase Genotypes and Parenting Influence on Long-Term Executive Functioning After Moderate to Severe Early Childhood Traumatic Brain Injury: An Exploratory Study — Kurowski et al., The Journal of head trauma rehabilitation (paywalled)
- saliva
- dna-genotek-oragene
- pediatric
- genotyping
2017
In an Irish cohort of 1516 participants, the rs2910164 variant in MIR146A was significantly associated with differentiated thyroid cancer (per allele OR = 1.59, P = 0.002) but not breast cancer. DNA extracted from saliva collected using Oragene 575 kits yielded successful genotyping, supporting decentralised screening for cancer predisposition.
Investigating the association of rs2910164 with cancer predisposition in an Irish cohort — McVeigh et al., Endocrine connections
- saliva
- dna-genotek-oragene
- genotyping
2017
Among 148 Marshallese adults recruited through community-based participatory research, 95.5% provided a 2 mL saliva specimen using an Oragene DNA self-collection kit and 96.6% agreed to future contact, demonstrating high acceptability of patient-centric, decentralised genetic sampling in an underserved population with disproportionate type 2 diabetes burden.
Leveraging community-based participatory research capacity to recruit Pacific Islanders into a genetics study — McElfish et al., Journal of community genetics (paywalled)
- saliva
- dna-genotek-oragene
- self-collection
- acceptability
- genotyping
2016
With Oragene DISCOVER self-collection, saliva SNP-array genotypes matched blood at 99.996% concordance; about 6% of samples failed on low yield, so an occasional repeat should be expected.
Saliva DNA quality and genotyping efficiency in a predominantly elderly population — Gudiseva et al., BMC Medical Genomics
- dna
- venous-agreement
- stabilised
- blood
- dna-genotek-oragene
- validation
- saliva
- genotyping
2016
ORAcollect saliva matched blood at 97.9% overall variant concordance on a hereditary-cancer NGS panel, rising to 100% for protein-coding variants, supporting self-collected saliva for germline testing.
Validation of saliva as an alternative specimen for detecting hereditary breast-cancer mutations by next-generation sequencing — Meghnani et al., International J. Genomics
- dna
- venous-agreement
- stabilised
- blood
- dna-genotek-oracollect
- validation
- saliva
- genotyping
2016
An evaluation of five saliva collection kits found that only Norgen and Stratec achieved DNA yields comparable to Oragene of 30 µg or more, whilst Oasis was the easiest for sample collection. All commercial kits outperformed an in-house protocol, offering viable, cost-effective options for decentralised sampling.
Comparative Study of Five Commercially Available Saliva Collection Kits for DNA Extraction — Deeley et al., Clinical laboratory (paywalled)
- dna-genotek-oragene
- liquid
- validation
- saliva
- genotyping
2016
Saliva collected with the Oragene DISCOVER kit from 30 patients with pheochromocytoma or paraganglioma produced DNA concentrations comparable to paired venous blood, though with slightly lower purity from protein contamination. Saliva is a viable alternative to blood for germline screening of SDHB and SDHD mutations in this population.
SDH Subunit Mutation Status in Saliva: Genetic Testing in Patients with Pheochromocytoma — Osinga et al., Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme (paywalled)
- saliva
- dna-genotek-oragene
- venous-agreement
- genotyping
2016
DNA from dried blood spots extracted with a home-made buffer yielded more DNA than a commercial kit at similar quality, and duplex allele-specific qPCR accurately identified all HLA-DQ2 and DQ8 alleles in 558 children, reducing genotyping costs by 60 per cent for population-wide celiac disease and type 1 diabetes screening.
A population-wide applicable HLA-DQ2 and DQ8 genotyping using DNA from dried blood spots and duplex allele-specific qPCR amplification — Aguayo-Patrón et al., Scandinavian journal of clinical and laboratory investigation (paywalled)
- blood
- dried
- dbs
- pediatric
- economics
- genotyping
2015
The study identified a mutation in the amelogenin gene from saliva samples collected using self-collection kits, which showed a statistically significant correlation with high caries experience in children. These results suggest that non-invasive genetic screening from saliva could facilitate early risk assessment for dental caries.
Association of Amelogenin with High Caries Experience in Indian Children — Saha et al., The Journal of clinical pediatric dentistry (paywalled)
- saliva
- dna-genotek-oracollect
- self-collection
- pediatric
- genotyping
2014
A US survey of 3,400 adults aged 62 to 90 collected up to 15 biomeasures at home, including saliva, dried blood spots and urine, with Salivette and Oragene among the devices used, which shows that several patient-centric sampling methods can run together in home-based research.
Continuity and innovation in the data collection protocols of the second Wave of the National Social Life, Health, and Aging Project — Jaszczak et al., The journals of gerontology. Series B, Psychological sciences and social sciences (paywalled)
- actigraphy
- multimodal
- blood
- dbs
- cortisol
- dna-genotek-oragene
- self-collection
- dried
- bd-microtainer
- hormones
- liquid
- urine
- saliva
- biomarkers
- genotyping
2014
DNA concentration from whole saliva correlates positively with age, so children yield significantly less DNA than adults. This means saliva collection protocols for genetic studies must be adjusted for paediatric populations to ensure adequate DNA quantity for genotyping.
The effect of age on DNA concentration from whole saliva: implications for the standard isolation method — Gassó et al., American journal of human biology : the official journal of the Human Biology Council (paywalled)
- saliva
- dna-genotek-oragene
- validation
- pediatric
- genotyping
2014
This study genotyped two oestrogen receptor gene variants in DNA from saliva samples of Serbian women and found no association with premature ovarian failure. The use of Oragene kits for saliva collection shows a practical method for obtaining DNA in genetic research on reproductive conditions, though these specific markers appear uninformative in this population.
Lack of association between ESR1 gene polymorphisms and premature ovarian failure in Serbian women — Li et al., Climacteric : the journal of the International Menopause Society (paywalled)
- saliva
- dna-genotek-oragene
- fertility
- genotyping
2014
In 230 women, HPV detection in self-collected urine showed 90 per cent agreement with cervical sampling (κ=0.80), with 97 per cent concordance for high-risk types. High viral load in urine correlated with cytological abnormalities, suggesting urine self-sampling could enable decentralised cervical cancer screening with good accuracy.
Interest of human papillomavirus DNA quantification and genotyping in paired cervical and urine samples to detect cervical lesions — Ducancelle et al., Archives of gynecology and obstetrics (paywalled)
- urine
- self-collection
- genotyping
- hpv
- sti
2012
Oragene-stabilised saliva DNA agreed with blood at 98.7% of called markers on a pharmacogenetic array; saliva's lower overall call rate tracked its variable human-DNA content.
Genotyping Performance between Saliva and Blood-Derived Genomic DNAs on the DMET Array: A Comparison — Hu et al., PLoS ONE
- dna
- stabilised
- blood
- dna-genotek-oragene
- validation
- saliva
- genotyping
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