The Library
1530 papers on microsampling and monitoring, each with a finding paraphrased to our standard and labelled in one vocabulary. Every entry links to a legitimate copy; nothing is copied from an abstract.
Papers 1–100 of 734 labelled “self-collection”, newest first.
2026
In AML and CLL, 91% of VAMS venetoclax results fell within 20% of plasma after individualised haematocrit correction; in home sampling, 18 of 21 patients self-sampled independently and 76% of returned samples were analysable, which shows home microsampling is workable, though the authors ask for multicentre validation.
Clinical Validation of Venetoclax Volumetric Microsampling in Leukemia, with Whole-Blood-to-Plasma Conversion and Self-Microsampling Feasibility — Levens et al., Clinical Pharmacokinetics (paywalled)
- vams
- venous-agreement
- blood
- dbs
- tdm
- self-collection
- haematocrit
- dried
- oncology
- capillary
- validation
2026
Participants preferred the Omnigene and Zymo oral swabs for comfort and ease of use, whilst the Omnigene device yielded the highest median bacterial DNA concentration compared to the other devices. The results indicate that the choice of self-collection device impacts both patient acceptability and DNA yield for oral microbiome analysis.
Comparison of self-collected oral swabs for supragingival microbiome characterization using 16S rRNA gene amplicon sequencing — Rooney et al., Journal of microbiological methods (paywalled)
- acceptability
- stabilised
- self-collection
- microbiome
- saliva
2026
Saliva samples collected using the OMNIgene ORAL device and oral wash samples remain stable for microbiome diversity and relative abundance analyses for up to five years when stored at -80°C. This supports the use of these self-collection methods for long-term prospective biobanking and decentralised clinical studies.
Long-term stability at -80°C of oral wash and saliva samples for microbiome analyses — Slack et al., Microbiology spectrum (paywalled)
- stabilised
- dna-genotek-omnigene
- self-collection
- microbiome
- liquid
- validation
- saliva
2026
This meta-analysis found that HPV testing using self-collected vaginal and urine samples showed sensitivities of 88.6% and 81% for detecting cervical precancer. Using a standardised device for first-void urine increased sensitivity to 86.6%, supporting decentralised patient-centric screening, though data on specificity and specific commercial devices were not consistently reported.
Diagnostic Performance of HPV Testing Using Self-Collected Urine and Vaginal Samples for Detecting Cervical Precancer or Worse: A Meta-Analysis — Hsiao et al., The journal of obstetrics and gynaecology research (paywalled)
- urine
- first-void
- self-collection
- validation
- hpv
- sti
2026
DNA methylation markers in first-void urine effectively detect high-grade cervical lesions in HPV-positive women, with results similar to clinician-collected samples in those over 30. This enables reliable cervical cancer screening using self-collected urine, reducing the need for invasive follow-up procedures in decentralised settings.
Evaluating DNA methylation markers and extended HPV genotyping in first-void urine for detecting high-grade cervical lesions in HPV-positive women: a cross-sectional study — Tranberg et al., BMC medicine
- colli-pee
- first-void
- self-collection
- hpv
- urine
- biomarkers
- genotyping
2026
A study of 2500 women found 99.0% agreement between first-void urine and vaginal self-sampling for HPV detection using Cobas4800, with 98.1% of participants preferring urine. Although conducted in a resource-limited setting which may limit generalisability, these results support urine as a viable sample type for decentralised, patient-centric screening.
Comparative efficacy, feasibility and acceptability of HPV DNA testing on first-void urine versus self-collected vaginal samples: a real-world study in a resource-limited setting — Bose et al., BMJ global health
- urine
- first-void
- self-collection
- acceptability
- hpv
- sti
2026
This study found that self-collected vaginal swabs and first-void urine yielded comparable detection rates for vaccine-targeted high-risk HPV types, supporting the use of both patient-centric methods for decentralised surveillance. Vaginal swabs showed higher sensitivity for non-vaccine types, whereas urine sampling offers a non-invasive alternative.
Comparison of self-collected vaginal swabs and first-void urine for detection of human papillomavirus in sexually active girls and women in three South Asian countries — Telele et al., PloS one
- urine
- first-void
- self-collection
- hpv
- sti
2026
First-void urine and self-collected vaginal swabs showed similar sensitivity and specificity to clinician-collected cervical samples for high-risk HPV detection across two real-time PCR assays, supporting their use as decentralised, patient-collected alternatives; most women preferred first-void urine for regular cervical screening.
Comparative performance of first-void urine and self-collected vaginal swabs against clinician-collected cervical samples using 2 HPV real-time assays in Indian women — A et al., Journal of gynecologic oncology (paywalled)
- acceptability
- first-void
- sti
- self-collection
- hpv
- urine
2026
A study in two UK cities found that at-home first-void urine sampling for HPV screening achieved a 59% uptake among women aged 60-79. Telephone reminders increased response by 5% compared with text messages, showing that decentralised sampling can engage older women, though response rates varied by area-level deprivation and screening history.
The Use of First-Void Urine to Screen Women Aged 60-79 for HPV in the UK: The Catch-Up Screen Study — Rake et al., BJOG : an international journal of obstetrics and gynaecology
- first-void
- self-collection
- hpv
- urine
2026
First-void urine samples showed significantly higher detection rates of HPV-specific IgG antibodies compared to midstream urine, confirming the necessity of capturing the initial stream. The study found no significant difference between 10 mL and 20 mL collection volumes, indicating flexibility in device specifications for self-collection.
The importance of first-void urine for assessing HPV-specific antibodies: A comparison with midstream urine — Van Caesbroeck et al., Human vaccines & immunotherapeutics
- first-void
- sti
- self-collection
- serology
- hpv
- urine
2026
In a small proof-of-concept, first-void urine and cervicovaginal brushes yielded high-quality vaginal microbiome profiles in most participants, comparable to vaginal swabs, offering non-invasive, user-friendly alternatives for research; however, storage at room temperature altered microbial composition in some first-void urine samples, indicating a need for careful handling.
First-void urine and cervicovaginal brushes for vaginal microbiome profiling: a proof-of-concept study — Pinedo-Bardales et al., Microbiology spectrum (paywalled)
- first-void
- self-collection
- microbiome
- hpv
- urine
2026
This meta-analysis found that self-collected urine samples for HPV testing had lower sensitivity for detecting high-grade lesions compared to physician-collected cervical specimens. The use of a first-void collection device such as Colli-Pee was associated with marginally higher sensitivity than general urine sampling.
Accuracy of HPV Testing Using Self-collected Urine Compared With Physician-collected Cervical Specimen for HSIL or Worse — Chen et al., Journal of lower genital tract disease (paywalled)
- urine
- first-void
- colli-pee
- self-collection
- validation
- hpv
- sti
2026
This randomised sub-study found return rates of 10.4% for Colli-Pee, 10.1% for FLOQSwabs and 7.4% for Evalyn-Brush. All devices yielded sufficient DNA with low invalid rates, but the authors noted the study was limited by low overall participation.
Comparison of three different hpv self-sampling tools - a subanalysis of the prospective, randomized hannover self-collection study — Hempel et al., Archives of gynecology and obstetrics
- urine
- first-void
- colli-pee
- self-collection
- acceptability
- hpv
- sti
2026
At-home volumetric absorptive microsampling (VAMS) for anti-seizure medicines was feasible and reliable, with strong correlations to clinic VAMS and low bias for lacosamide, lamotrigine and levetiracetam; quantitative dried blood spot (qDBS) was a reliable alternative in the ambulatory setting, though older age reduced sampling quality.
Real-world evaluation of capillary microsampling for drug monitoring of anti-seizure medications — Cancellerini et al., Epilepsia (paywalled)
- vams
- venous-agreement
- acceptability
- blood
- qdbs
- tdm
- self-collection
- dried
- capillary
2026
This review found that volumetric microsampling devices, such as Mitra, HemaPEN, HemaXis DB10, and Tasso-M20, overcome haematocrit bias, whilst Telimmune plasma separation cards enable direct plasma collection without centrifugation. These technologies support patient-centric, decentralised sampling, though the authors note that clinical validation remains limited across different drugs and patient populations.
A Review of Blood-Based Microsampling Devices for Patient-Centered Application in Therapeutic Drug Monitoring — Huhn & Scherf-Clavel, Therapeutic drug monitoring (paywalled)
- vams
- volumetric
- acceptability
- neoteryx-mitra
- blood
- dbs
- tdm
- self-collection
- haematocrit
- dried
- capillary
- validation
2026
Analysis of self-collected stool samples from 309 participants demonstrated that proton pump inhibitor use is significantly associated with an enrichment of Streptococcus species in the gut. This confirms the suitability of decentralised self-sampling for conducting large-scale metagenomic analyses in population studies.
Gut Microbial Variations Associated With Proton Pump Inhibitor Use in the Boston Puerto Rican Health Study — Dinesh et al., Pharmacology research & perspectives
- stool
- self-collection
- microbiome
2026
Capillary dried blood spots, after haematocrit-dependent conversion, showed good agreement with plasma for 25-hydroxyvitamin D quantification, with 90 per cent of results within 20 per cent of plasma and substantial to almost perfect agreement in status classification, supporting reliable home self-collection for large-scale vitamin D monitoring.
Clinical validation of a DBS-based LC-MS/MS method for 25-hydroxyvitamin D: from lab sampling to home sampling — Heughebaert et al., Clinical chemistry and laboratory medicine (paywalled)
- venous-agreement
- blood
- dbs
- self-collection
- haematocrit
- dried
- capillary
- validation
- biomarkers
2026
Vaginal self-sampling achieved higher pooled sensitivity and specificity than urine self-sampling for detecting high-risk HPV, making it the preferred option, while urine self-sampling remains a useful non-invasive choice for under-screened populations.
Diagnostic Accuracy of Urine and Vaginal Self-Sampling for Detection of High-Risk Human Papillomavirus: A Systematic Review and Meta-Analysis — Rakhat & Aimagambetova, Viruses
- first-void
- sti
- self-collection
- hpv
- urine
- validation
2026
For decentralised testing, a study found dry vaginal self-samples using Copan FLOQSwabs stored up to two weeks at room temperature maintain DNA quality. However, first-void urine collected with the Colli-Pee device may be less sensitive for HPV detection, showing lower positivity and higher cycle threshold values, median Ct 30 versus 27 for other samples.
Evaluation of the Quality and Suitability of Self-Collected Vaginal and Urine Samples for Human Papillomavirus Testing: A Prospective Matched Study — Chu et al., BJOG : an international journal of obstetrics and gynaecology
- colli-pee
- first-void
- sti
- self-collection
- dried
- hpv
- urine
- validation
2026
The study found that testing for ASCL1/LHX8 DNA methylation in at-home collected first-void urine can detect most cervical cancers and high-grade precancers, supporting a fully molecular screening pathway without a clinical visit.
Clinical performance of ASCL1/LHX8 DNA methylation on first-void urine to screen for cervical cancer — Van Keer et al., Communications medicine
- colli-pee
- first-void
- self-collection
- hpv
- liquid-biopsy
- urine
- biomarkers
2026
The study found that self-collection of dried blood spots and other samples using at-home kits was a useful and cost-effective method for screening a large cohort for sexually transmitted infections outside a clinic. This demonstrates the feasibility of decentralised, patient-centric sampling for population-level infectious disease surveillance.
Prevalence of chlamydial, gonococcal and syphilis positivity by anatomical site and sex via self-collected biospecimens using at-home testing kits among a large and diverse cohort of men and women enrolled in the MACS/WIHS Combined Cohort Study (MWCCS) in the USA — Mimiaga et al., Sexually transmitted infections (paywalled)
- blood
- sti
- dbs
- self-collection
- dried
- serology
- bd-microtainer
- urine
2026
The study found that although participants preferred patient-centric microsampling devices for home use, the agreement with venous plasma for measuring CRP and cytokines was inconsistent, indicating that further validation is required before these methods replace standard venipuncture.
Limited agreement of cytokines and CRP through patient-centric microsampling compared to venipuncture in healthy adults — Tuttle et al., Bioanalysis (paywalled)
- dct
- venous-agreement
- acceptability
- blood
- dbs
- self-collection
- dried
- biomarkers
2026
The study demonstrated the feasibility of a fully decentralised design by successfully recruiting 37 participants and completing follow-up for self-collected stool samples without requiring on-site visits.
Perioperative Antibiotic Prophylaxis in Cesarean Section and the Maternal Gut Microbiome: Protocol for a Remote Observational Cohort Study — Feles & Mattner, JMIR research protocols
- stool
- self-collection
- dct
- microbiome
2026
This pilot study found that mailing self-collection kits to endometrial cancer survivors was feasible and acceptable, whilst also observing that chemotherapy or radiation reduced beneficial vaginal bacteria compared to surgery alone.
Stool and vaginal microbiome profiles patterns among Black and White endometrial cancer survivors: A pilot study in North Carolina — Jin et al., PloS one
- stool
- self-collection
- acceptability
- microbiome
2026
Self-sampling for HPV testing using urine and swab devices achieved high DNA detection rates, 92.1-99.7%, and very high participant acceptance, 99.1%, in a primary care population, supporting decentralised screening in low-resource settings.
Population-based self-sampling under primary care conditions - a possible approach for cervical cancer screening in Indonesia (IndoCerCa study) — Wenang et al., Reproductive health
- urine
- self-collection
- validation
- acceptability
- hpv
- sti
2026
This retrospective analysis of over 600,000 online postal self-sampling orders found that whilst return rates for urine samples were moderate to high, the return of processable blood samples was significantly lower and varied by age and deprivation level.
Factors associated with the online postal self-sampling testing cascade in England, 2022: a retrospective observational study of routinely collected service-level healthcare data — Gibbs et al., Sexually transmitted infections (paywalled)
- blood
- sti
- self-collection
- serology
- urine
2026
Self-collected vaginal samples demonstrated comparable sensitivity to clinician-collected specimens for detecting high-grade squamous intraepithelial lesions, whereas urine and menstrual blood samples showed lower sensitivity despite moderate concordance for human papillomavirus detection.
HPV Detection in Clinician-Collected, Self-Collected Vagina, Urine, and Menstrual Blood Samples — Ho et al., Journal of lower genital tract disease (paywalled)
- blood
- urine
- self-collection
- hpv
- sti
2026
Midstream urine self-collection demonstrated adequate sensitivity for Chlamydia trachomatis screening in asymptomatic patients, although it was less sensitive than vaginal swabs in women, and the study confirmed that nucleic acids in neat urine remain stable for up to seven days when stored at 4°C.
The potential use of midstream urine samples for diagnosing Chlamydia/Gonorrhoea NAAT in male and female patients, and the pre-analytical storage conditions in neat urine specimens — Ilardo et al., The new microbiologica (paywalled)
- sti
- self-collection
- liquid
- urine
- validation
2026
This study found strong agreement between self-collected urine samples tested with the INDICAID HPV assay and clinician-collected swabs tested with the BD Onclarity assay for detecting high-risk HPV. The results suggest that urine-based self-collection offers a reliable alternative for cervical cancer screening, potentially improving access for women who face barriers to standard care.
Agreement between INDICAID™ HPV (human papillomavirus) Urine Test and BD Onclarity™ HPV Assay in detection of high-risk HPV in self-collected urine samples — Yung et al., Journal of gynecologic oncology (paywalled)
- sti
- self-collection
- hpv
- liquid
- urine
- validation
2026
Community pharmacy-based testing and treatment for chlamydia and gonorrhoea using self-collected first-catch urine was highly acceptable to users and successfully identified new cases, with pharmacists efficiently prescribing antibiotic treatment. This supports decentralised sampling by showing that asymptomatic STI testing can be delivered through self-collection in non-clinical settings with good uptake and patient satisfaction.
Implementation of community pharmacy-based testing and treatment for Chlamydia trachomatis and Neisseria gonorrhoeae in Nova Scotia (Swab-Rx study) — d'Entremont-Harris et al., Journal of the American Pharmacists Association : JAPhA (paywalled)
- urine
- first-void
- self-collection
- acceptability
- sti
2026
This meta-analysis found that urine self-sampling for HPV detection had significantly lower sensitivity for high-grade lesions compared to vaginal and cervical samples, though specificity remained comparable. Despite the reduced diagnostic accuracy, the non-invasive and acceptable nature of urine sampling supports its use as a decentralised option to improve screening uptake.
A systematic review and meta-analysis of diagnostic accuracy of urine self-sampling for human papillomavirus detection in cervical cancer screening — Nath et al., Journal of medical screening (paywalled)
- acceptability
- sti
- self-collection
- hpv
- urine
- validation
2026
Genital swabs demonstrated a significantly higher human papillomavirus positivity rate than self-collected urine samples or urethral swabs in men, suggesting that urine may be a less sensitive matrix for screening in this population.
Urine sample for HPV detection in men: is it a valid and non-invasive diagnostic alternative? — Sucato et al., Microbiology spectrum
- sti
- self-collection
- hpv
- urine
- validation
2026
This study found that self-collected vaginal dry swabs provided noninferior sensitivity for detecting high-grade cervical lesions compared to practitioner-collected samples, although specificity was lower.
Clinical Validation of the Roche cobas and cobas 4800 Human Papillomavirus Tests on Self-Collected Vaginal Dry Swabs versus Practitioner-Collected Cervical Specimens Using the VALHUDES Protocol — Hawkes et al., The Journal of molecular diagnostics : JMD (paywalled)
- sti
- self-collection
- dried
- hpv
- validation
2026
Dried urine strips demonstrated high diagnostic accuracy and stability for chlamydia and gonorrhea detection compared to standard urine samples. This method supports decentralised screening by allowing self-collection and ambient temperature transport without compromising sample integrity.
Development and evaluation of dried urine strip for genital chlamydia and gonorrhea testing — Gibbons et al., Journal of clinical microbiology
- sti
- self-collection
- dried
- urine
- validation
- genotyping
2026
Self-collected HPV testing was highly acceptable to transgender men with a cervix, and most participants preferred urine-based self-sampling over vaginal sampling, suggesting urine self-collection could help overcome barriers to cervical screening in this group.
Genital human papillomavirus detection in self-samples from transgender men — Vervalcke et al., European journal of obstetrics, gynecology, and reproductive biology (paywalled)
- urine
- self-collection
- acceptability
- hpv
- sti
2026
Single unstimulated whole saliva measurements show high physiological variability, but averaging repeated self-collected samples, particularly in the evening, improves diagnostic reliability. This validation supports the implementation of home-based saliva testing for salivary gland dysfunction.
Repeated Unstimulated Whole Saliva Collection: A Reliable Approach to Improve Diagnostic Accuracy — Musella et al., Journal of oral rehabilitation
- saliva
- liquid
- self-collection
- validation
2026
This study validated a low-cost 3D-printed smartphone attachment and paper sensor for measuring glucose, uric acid and cholesterol in saliva, demonstrating high correlation with standard ELISA results in a small clinical cohort. The authors suggest this platform offers a scalable solution for decentralised diabetes management by balancing sensitivity with affordability.
Nanostructured zinc-coordination supraparticles on cellulose fibers: A 3D-Printed μ-FAD integrated smartphone platform for multiplexed salivary metabolic monitoring — Yang et al., Biosensors & bioelectronics (paywalled)
- dct
- economics
- metabolome
- self-collection
- liquid
- validation
- saliva
2026
This study used home self-collected saliva samples to successfully monitor cytokines and cortisol in mothers and infants, finding that a community singing intervention significantly reduced salivary interleukin-6 levels in mothers with postnatal depression.
Community singing intervention reduces maternal salivary cytokines and enhances maternal-infant cortisol synchrony in postnatal depression: biological findings from the SHAPER-PND trial — Kirkpatrick et al., Brain, behavior, and immunity (paywalled)
- dct
- cortisol
- self-collection
- pediatric
- hormones
- liquid
- saliva
- biomarkers
2026
At-home saliva sampling for cortisol was feasible over 12 days in two people with poststroke aphasia, with the cortisol awakening response remaining consistent across days and weeks.
Intraindividual Variability of the Cortisol Awakening Response, Sleep Dynamics, Stress, and Emotion in Two Persons With Poststroke Aphasia — Laures-Gore et al., Journal of speech, language, and hearing research : JSLHR (paywalled)
- cortisol
- self-collection
- hormones
- liquid
- saliva
2026
Self-collected salivary progesterone and the ratio of estradiol to progesterone showed strong agreement with serum levels, supporting the use of saliva as a noninvasive matrix for monitoring the menstrual cycle.
Salivary estradiol and progesterone across the menstrual cycle: Association and agreement with serum concentrations — Goldenstein et al., Physiological reports
- venous-agreement
- blood
- self-collection
- fertility
- hormones
- saliva
2026
Using a synthetic swab for saliva collection gave results closest to no swab for both resting and stimulated samples, indicating minimal pre-analytical interference. The widest metabolite coverage was achieved with ACN:MeOH at 1:1 v/v and a ZIC-HILIC column for polar metabolites plus a C18 column for non-polar metabolites, and resting versus stimulated saliva yielded distinct metabolic profiles that may provide complementary clinical insights.
Impact of Selected Pre-Analytical and Analytical Factors on Untargeted Salivary Metabolomics — Michorowska et al., International journal of molecular sciences
- metabolome
- self-collection
- liquid
- validation
- saliva
2026
The study found that self-collected dried saliva on FishburneTabs achieved 92% accuracy for viral RNA detection compared to standard liquid saliva samples. This method supports decentralised testing by enabling reliable sample storage and transport for upper respiratory infections.
Validation of Dried Saliva for Molecular Diagnostics — Mora et al., ACS measurement science au
- self-collection
- dried
- serology
- validation
- saliva
2026
This study found that salivary 11-dehydrodexamethasone correlates strongly with serum dexamethasone, unlike salivary dexamethasone which shows poor agreement. This validation suggests patients could self-collect saliva samples at home to verify dexamethasone absorption for the overnight suppression test.
The Utility of Salivary 11-Dehydrodexamethasone as a Marker of Dexamethasone Absorption — Marshall et al., The Journal of clinical endocrinology and metabolism (paywalled)
- venous-agreement
- tdm
- cortisol
- self-collection
- hormones
- liquid
- validation
- saliva
2026
This study validated a lateral flow fluorescence assay using quantum dots for saliva and europium nanoparticles for serum to detect cortisol within physiological ranges. The test operates in 15 minutes with a handheld reader, supporting point-of-care and at-home monitoring without a cold chain.
Ultrasensitive de novo Protein Sandwich Lateral flow Fluorescence Assay for Cortisol in Saliva and Serum using Quantum dots and Europium Nanoparticles — Bruno et al., Journal of fluorescence (paywalled)
- blood
- saliva
- liquid
- self-collection
- validation
- hormones
- cortisol
2026
The study determined that an at-home saliva collection protocol using the passive drool method was feasible for Black women with histories of abuse, with 84% of participants completing at least one full day of adherent sampling. While the decentralised approach yielded usable cortisol data, women with histories of forced sex exposure showed lower protocol adherence scores.
Repeat At-Home Saliva Collection to Measure Cortisol Awakening Response (CAR): Protocol Feasibility Study Among Black Women With Histories of Abuse — Tsuyuki et al., Interactive journal of medical research (paywalled)
- dct
- acceptability
- cortisol
- self-collection
- liquid
- saliva
2026
The study validated a semi-quantitative protocol for Epstein-Barr virus serology using dried blood spots, demonstrating 98.8% sensitivity and 96.5% specificity compared to paired venous serum samples. The successful validation in a self-sampling cohort confirms the suitability of this patient-centric microsampling approach for large-scale seroprevalence studies and decentralised trials.
A dried blood spot protocol for high-throughput semi-quantitative analysis of Epstein-Barr Virus VCA IgG and EBNA IgG serologies based on the Roche Elecsys system — Rubio-Acero et al., Virology journal
- blood
- dried
- capillary
- dbs
- self-collection
- validation
- venous-agreement
- serology
2026
A machine learning model called Remote Control was trained on 2685 blood samples to predict change due to instability, enabling accurate calibration of results to approximate the time zero value at collection. With calibration, unprocessed whole blood could be transported for up to 9 days under ambient conditions and temperatures between 3.4 and 47.4 degrees Celsius, achieving agreement with CLIA TEa between 98.1 and 100 per cent and expanding the catalog of tests available for at-home collection.
Prolonging Sample Stability with Machine Learning Expands the Catalog of Tests Available for Mail-In Capillary Blood Collected At-Home — O'Meara et al., Analytical chemistry (paywalled)
- dct
- blood
- self-collection
- capillary
- liquid
- validation
- biomarkers
2026
This proof-of-concept study demonstrated that patients with inflammatory bowel disease could successfully perform capillary blood microsampling at home with high analytical success rates, and a majority preferred this decentralised approach over hospital venous draws.
Implementation of a Capillary Blood Self-Sampling Technique at Home for Monitoring of Patients With IBD — Schuurman et al., Inflammatory bowel diseases
- acceptability
- multimodal
- blood
- rpm
- self-collection
- capillary
- liquid
2026
This UK consensus opinion outlines how clinical laboratories can validate self-collected capillary blood sampling against venous reference standards to achieve accreditation and facilitate the shift towards community-based patient care.
UK recommendations for the validation and adoption of capillary blood testing within the routine clinical laboratory: Consensus opinion from the LabMed patient-centred testing and sampling (PaCTS) group — Woolley et al., Annals of clinical biochemistry (paywalled)
- venous-agreement
- blood
- standards
- self-collection
- capillary
- liquid
- validation
2026
Capillary blood samples collected by staff or self-collected by participants showed strong correlation and clinically acceptable agreement with venipuncture for influenza haemagglutination inhibition titers. The small differences observed were not clinically meaningful, and adequate sample volume was achieved in most attempts, supporting the feasibility of decentralised serological testing.
Comparison of influenza hemagglutination inhibition titers from capillary blood versus venipuncture — Rick et al., Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology (paywalled)
- blood
- liquid
- capillary
- self-collection
- validation
- venous-agreement
- serology
2026
This study found strong concordance between capillary samples collected via the Tasso device and standard venous draws for VirScan serology, indicating that self-collected samples are a practical alternative for decentralised research. The authors advise against interchanging these collection methods within a single longitudinal study to avoid introducing technical variability.
Assessing VirScan serosurvey epitope profiling variability between in-clinic venous blood draw and capillary blood self-sampling device — Sircy et al., Microbiology spectrum
- dct
- venous-agreement
- blood
- self-collection
- serology
- capillary
- liquid
2026
Self-collected capillary blood samples posted by standard mail showed high concordance with couriered venous samples for HbA1c, creatinine and lipid parameters, supporting their use for remote monitoring in diabetes management and screening.
Concordance of HbA1c, creatinine, LDL cholesterol, HDL cholesterol, and total cholesterol between venous and self-collected capillary blood samples sent by mail — Hoffmeister et al., Journal of diabetes investigation
- venous-agreement
- blood
- self-collection
- capillary
- liquid
- validation
2026
In a 20-person proof-of-concept pilot among veterans with HIV, remote self-collection of dried blood spots for phosphatidylethanol monitoring was feasible and acceptable, with high return and analysis rates and positive feedback; a small first step toward decentralised alcohol biomarker monitoring rather than proof of it.
Remote alcohol biomarker monitoring to promote drinking reductions among people with HIV: A proof-of-concept pilot study — Sheinfil et al., Journal of substance use and addiction treatment (paywalled)
- acceptability
- blood
- dbs
- self-collection
- dried
- biomarkers
2026
Self-collected dried blood spot specimens for phenylketonuria monitoring showed very poor quality initially but improved substantially over a decade with training and education, reducing measurement error and the risk of incorrect clinical interpretation.
Improving self-collected dried blood spot specimens for phenylketonuria monitoring: a 10-year computer vision review of dried blood spot specimen quality — Flynn et al., Clinica chimica acta; international journal of clinical chemistry (paywalled)
- blood
- dbs
- self-collection
- dried
- validation
2026
In a pilot mixed-methods study of youth with HIV, mailed HemaSpot-HF kits enabled home-based dried blood spot collection that participants found feasible and acceptable, supporting remote viral load monitoring and a self-management model for decentralised care.
An Examination of Perceptions and Usage of Dried Blood Spot Biosampling Technology for HIV Viral Load Collection Among Youth with HIV — Gurung et al., AIDS and behavior (paywalled)
- blood
- dried
- dbs
- self-collection
- acceptability
- dct
- serology
2026
Enhanced visual and textual guidance significantly improved the quality of dried blood spots self-collected by children and adolescents, increasing the proportion of acceptable cards from 47.6% to 86.6%, which supports the feasibility of home sampling for therapeutic drug monitoring.
Optimizing Dried Blood Spot Sampling for Children and Adolescents With Autism Spectrum Disorder — Ringeling et al., Therapeutic drug monitoring
- blood
- dried
- dbs
- self-collection
- pediatric
- tdm
2026
The study found that quantitative dried blood spot sampling provided high clinical agreement for tacrolimus and creatinine monitoring, with patients rating the self-collection devices as user-friendly. These results support the feasibility of decentralised therapeutic drug monitoring for immunosuppressants.
Patient-centric capillary dried blood spot sampling for tacrolimus and creatinine monitoring in clinical practice — De Baets et al., Clinical chemistry and laboratory medicine (paywalled)
- blood
- dried
- capillary
- dbs
- qdbs
- self-collection
- venous-agreement
- acceptability
- tdm
- immunosuppressants
2026
This pilot study demonstrated that a fully remote web-based testing programme for sexually transmitted and blood-borne infections was feasible and acceptable overall, although participants encountered specific collection challenges with the dried blood spot component.
Comprehensive at-home sexually transmitted and blood borne infection (STBBI) testing program: A pilot study — Christensen et al., International journal of STD & AIDS
- blood
- urine
- dried
- dbs
- self-collection
- acceptability
- sti
2026
Although most kidney transplant recipients successfully collected capillary blood samples at home, haemolysis and transport conditions affected analyte stability. Agreement with venous sampling was acceptable for haemoglobin and creatinine, but potassium and haematocrit exceeded total allowable error limits.
At-home blood collection for clinical chemistry analyses in a kidney transplant population: a feasibility study — Hoekstra et al., Clinical chemistry and laboratory medicine (paywalled)
- blood
- liquid
- capillary
- bd-microtainer
- self-collection
- validation
- venous-agreement
2026
This developer study reports that a self-collection kit interfacing with a BD Microtainer produced RNA of sufficient quality and yield for transcriptomic analysis in a pilot group and a longitudinal rheumatology cohort. Most participants found the device easy to use, supporting its utility for decentralised blood sampling.
To the homeRNAmax: Developing an Improved Blood Self-Collection and Stabilization Platform for Remote Transcriptomic Studies — Eakman et al., Analytical chemistry (paywalled)
- dct
- blood
- self-collection
- bd-microtainer
- liquid
- validation
- biomarkers
2026
This study found that home-based multi-pathogen self-sampling, including urine collection, was feasible and highly acceptable to women in Zambia, with the majority preferring home visits over clinic attendance.
Acceptability and feasibility of one-stop home-based genital self-sampling for female genital schistosomiasis, human papilloma virus and self-testing for trichomonas and HIV: the Zipime Weka Schista study in Zambia — Ndubani et al., BMC women's health (paywalled)
- urine
- self-collection
- acceptability
- hpv
- sti
2026
Volumetric microsampling can enable patient-centred therapeutic drug monitoring with high patient preference and acceptable method validation for many drugs, but conversion from capillary to plasma and agreement with venous sampling varies by analyte and requires careful validation.
Volumetric Microsampling for Patient-Centric Therapeutic Drug Monitoring in Clinical Pharmacology: A Scoping Review — Tummala et al., Journal of clinical pharmacology (paywalled)
- volumetric
- venous-agreement
- acceptability
- blood
- tdm
- self-collection
- haematocrit
- dried
- capillary
- validation
2026
In a large study using self-collected capillary blood, current vaping and smoking were independently associated with lower levels of anti-Müllerian hormone, a marker of ovarian reserve. This demonstrates the utility of decentralised capillary sampling for large-scale epidemiological research on reproductive health.
E-cigarette use (vaping) and cigarette smoking are associated with reduced markers of ovarian reserve: a cross-sectional study of 16,087 women — Getreu et al., BMC women's health (paywalled)
- blood
- self-collection
- capillary
- fertility
- hormones
2026
Capillary finger-stick dried blood spots demonstrated strong analytical agreement with venous serum for prostate-specific antigen (R² = 0.987) and remained stable for 31 days across a wide temperature range. This less invasive microsampling approach enables at-home self-collection, supporting decentralised screening and tele-diagnostics for prostate cancer.
Accessible Prostate-Specific Antigen Testing through Finger-Stick Dried Blood Spots and Routine Laboratory Analyzers — van Vugt et al., The journal of applied laboratory medicine (paywalled)
- blood
- dried
- capillary
- dbs
- self-collection
- validation
- venous-agreement
- haematocrit
- biomarkers
2026
In a study of 46 perinatal nicotine users, dried blood spots and saliva were used weekly to measure reproductive hormones, finding that lower postpartum estradiol and greater peripartum declines in oxytocin were associated with increased nicotine craving and use. This demonstrates the feasibility of decentralised microsampling and remote surveys for longitudinal hormone tracking in vulnerable populations.
Exploring hormonal influences on nicotine craving and use across the perinatal period: A prospective longitudinal study — Allen et al., Drug and alcohol dependence reports (paywalled)
- blood
- dbs
- cortisol
- self-collection
- dried
- fertility
- hormones
- saliva
2026
In a cohort of 62 participants evaluating home self-collection with the TassoPlus device, 38 returned samples, with 29% excluded due to insufficient plasma volume below 200 ΔL. Although viral load measurements in adequate samples correlated well with conventional testing (r = 0.800), the high failure rate and missed detection in low-volume viremic samples indicate that further technical refinements are necessary before clinical adoption.
Feasibility and reliability of decentralized HIV-1 viral load monitoring on self-sampled blood — Mendes de Leon et al., PloS one
- blood
- liquid
- capillary
- self-collection
- validation
- venous-agreement
- acceptability
- serology
2026
In a feasibility randomised controlled trial with 28 adults aged 65 years, 62% successfully self-collected finger-prick capillary blood samples for influenza antibody and vitamin D measurement. While overall study procedures were acceptable, the capillary sampling method requires refinement before wider deployment in decentralised diagnostics for older adults.
PROTECTIVE-D-a feasibility randomised controlled trial examining the effect of a positive mood intervention and vitamin D supplementation on the immunological responses to influenza vaccination in older adults — Royal et al., Pilot and feasibility studies (paywalled)
- blood
- capillary
- self-collection
- acceptability
- dct
2026
Menstrual blood offers a noninvasive, patient-centric matrix for detecting endometriosis, cervical cancer, and hormonal disorders through self-collected samples. Wearable in-pad biosensors enabling real-time monitoring and long-term tracking could transform fertility evaluation and early disease detection, though standardisation and large-scale validation remain critical gaps.
Beyond waste: menstrual blood as a powerful diagnostic tool for women's health — Shafiq et al., Annals of medicine and surgery
- blood
- self-collection
- fertility
- hormones
- wearable
- multimodal
2026
In a large real-world cohort of pregnancy planners using home urine tests, sensitivity was lower than expected before the expected period, with false negatives of 12.7% at 2 days, 21.4% at 3 days and 46.4% at 4 days before menses; sensitivity rose sharply thereafter to over 99% by 4 days after the expected period, and for any given test day, longer menstrual cycles were associated with higher sensitivity, especially among early testers.
Home pregnancy test sensitivity by test timing and cycle length with real-world use among pregnancy planners who conceived — Sundermann et al., Fertility and sterility (paywalled)
- urine
- self-collection
- fertility
2026
Low-volume blood collection devices enable frequent, longitudinal sampling at home with reduced invasiveness, thereby improving participant retention in patient-centric studies. This facilitates decentralised biomarker monitoring for tracking disease progression and understanding physiological responses to diet, medication and physical activity.
Low-volume collection devices for longitudinal biomarker monitoring in patient-centric sampling settings — Simon-Guth et al., Bioanalysis (paywalled)
- blood
- self-collection
- validation
- dct
- biomarkers
2026
A female participant using the Tasso+ capillary self-blood collection device developed a gaping lesion at the application site that required surgical treatment and left a permanent scar, highlighting an unexpected safety issue and the need for further safety evaluation of self-administered blood collection systems.
Unexpected scarring following use of capillary self-blood collection device: A case report and discussion of device design — Müller et al., The journal of vascular access
- blood
- capillary
- self-collection
2026
Postnatal women view the six-week check-up as a window of opportunity for cervical screening via urine self-sampling, though some feel it may be too soon after delivery. The study reveals women's health is perceived as neglected compared with infant care, supporting feasibility of a trial to test early postnatal screening uptake.
Investigating the Acceptability of Cervical Screening and Self-Sampling in Postnatal Women at the 6-Week Postnatal Check-Up: A Qualitative Study — Newhouse et al., Health expectations : an international journal of public participation in health care and health policy
- urine
- self-collection
- acceptability
- hpv
2026
Statewide mail-based serosurveys using dried blood spot cards showed high spike antibody positivity and rising neutralising antibodies over time, with no differences by socio-demographic factors, supporting the feasibility of decentralised self-sampling for population infection surveillance.
Population-based serosurveys for SARS-CoV-2 transmission 2021-2022, Massachusetts USA — Cramer et al., Vaccine (paywalled)
- blood
- dried
- dbs
- self-collection
- serology
2026
In a nationwide survey of 1047 Belgian adults, at-home VAMS achieved a 63% participation-to-analysis completion rate with 16% of samples excluded due to insufficient quality. While dietary intake suggested adequate thiamine consumption, 11% of participants had blood thiamine diphosphate concentrations below the reference threshold, showing the utility of remote microsampling for identifying true nutritional status.
Thiamine status in Belgian adults assessed by volumetric absorptive microsampling: a nation-wide cross-sectional survey — Heughebaert et al., The American journal of clinical nutrition (paywalled)
- blood
- dried
- capillary
- vams
- neoteryx-mitra
- self-collection
- biomarkers
2026
A triple-channel immunochromatographic system using quantum dots detected influenza A and B and SARS-CoV-2 nucleoproteins in saliva with limits of detection from 0.227 to 0.348 ng/mL. Testing of 15 influenza A patients and 20 healthy controls showed 100% sensitivity and 95.2% specificity, indicating potential for accurate home-based respiratory virus screening.
A multiplexed three-channel detection system for rapid home-based diagnosis of respiratory viruses — Huang et al., Talanta (paywalled)
- saliva
- self-collection
- serology
2026
Among 454 postnatal women, 74.4 per cent would be more likely to undergo cervical screening if offered urine self-sampling for HPV at six weeks postnatal, and 54 per cent preferred this method to conventional clinician-taken samples. This indicates high acceptability of patient-collected urine for decentralised HPV screening in the postnatal period, which could improve uptake when integrated into routine postnatal care.
Investigating the acceptability of cervical screening, using conventional clinician-taken cervical samples or urine self-sampling, at 6 weeks postnatal: A cross-sectional questionnaire — Cullimore et al., Journal of medical screening
- urine
- self-collection
- acceptability
- hpv
2026
Salivary HPV DNA testing achieved 91.7% sensitivity and 100% specificity against oropharyngeal swab in patients with oral cavity cancer, demonstrating potential for non-invasive self-collection screening programmes and long-term monitoring of HPV-driven disease.
Application of a Saliva-Based Liquid Biopsy for the Detection of HPV in Patients With Oral Cavity Squamous Cell Carcinoma (OCSCC) — Bulfoni et al., Head & neck
- saliva
- self-collection
- validation
- hpv
- liquid-biopsy
2026
The Phase HPV Urine Test detected 14 high-risk HPV types from first-void urine samples, showing 93 per cent concordance with the Roche cobas 4800 reference assay after sequencing adjudication. The test demonstrated high precision, a low limit of detection, and ten-day stability at ambient temperature, supporting non-invasive, self-collected screening to improve access and participation.
Performance of a novel, urine-based test for the detection of cervical human papillomavirus infection — Manjeshwar et al., Journal of clinical microbiology
- urine
- first-void
- self-collection
- validation
- hpv
- sti
2026
Dried blood spot collection proved feasible during parabolic flight, with seventeen of twenty volunteers successfully providing samples for caffeine pharmacokinetic profiling. The method yielded stable metabolic ratios between ground and weightless conditions, and participants reported high satisfaction, suggesting DBS could support therapeutic drug monitoring in remote or extreme environments such as long-term spaceflight.
Feasibility of dried blood spot collection for caffeine pharmacokinetic studies in microgravity: Insights from parabolic flight campaigns — Derobertmasure et al., British journal of clinical pharmacology
- blood
- dried
- dbs
- self-collection
- acceptability
- tdm
- genotyping
2026
In women with abnormal cytology, hrHPV testing and PAX1/ZNF671 methylation were assessed across paired self-collected urine and vaginal samples versus clinician cervical scrapes. Methylation markers showed high area under the ROC curve for CIN3+ and strong correlation with lesion severity, and the optimal PAX1/ZNF671 panel achieved high sensitivity for CIN2+ in cervical samples but lower sensitivity in urine and vaginal samples, indicating cervical samples are optimal for methylation testing while urine and vaginal self-collection may be useful for hrHPV triage.
Comparative performance of hrHPV testing and PAX1/ZNF671 methylation in triaging women with abnormal cytology: a study of paired urine, vaginal and cervical scrape samples — Wang et al., Frontiers in oncology
- urine
- self-collection
- hpv
- sti
2026
The Alinity m STI assay achieved strong agreement with comparator nucleic acid amplification tests across female urogenital specimens, with κ scores of 0.84 to 0.99. Urine and self-collected vaginal swabs showed high positive agreement (≥99.2% and ≥98.0% respectively), validating their reliability for decentralized STI screening.
Evaluation of Alinity m STI Assay for Simultaneous Detection of Chlamydia trachomatis , Neisseria gonorrhoeae , Trichomonas vaginalis , and Mycoplasma genitalium in Female Urogenital Specimens — Gentil et al., Sexually transmitted diseases
- urine
- self-collection
- validation
- sti
2026
A paired-sample study of postnatal cervical screening proved feasible with high attendance and low test inadequacy. Urine self-sampling for HPV showed lower sensitivity (60% at six weeks) than clinician-taken samples, suggesting it may be less reliable in this population.
Comparison of Cervical Screening at 6- and 12-Weeks Postnatal: A Paired-Sample Feasibility Study — Cullimore et al., BJOG : an international journal of obstetrics and gynaecology (paywalled)
- urine
- self-collection
- acceptability
- hpv
- sti
2026
In a multicentre European study the Papilloplex HR-HPV assay showed similar clinical sensitivity for CIN2+ on self collected urine and vaginal swabs compared with clinician taken cervical samples, while clinical specificity was similar for urine but lower for vaginal swabs; cut off optimisation restored specificity for vaginal swabs without compromising sensitivity.
Clinical performance assessment of the Papilloplex HR-HPV assay on self-taken urine and vaginal swab samples: findings from a multicentre European study — Cuschieri et al., Journal of clinical pathology (paywalled)
- urine
- self-collection
- validation
- hpv
- sti
2026
The COVID-19 pandemic accelerated adoption of decentralised testing and self-collected saliva specimens, but revealed challenges with variable diagnostic accuracy and lack of internationally standardised processing protocols. Stricter regulatory oversight and robust diagnostic stewardship are needed to balance broad access with clinical performance.
Beyond the laboratory: how COVID-19 reshaped specimen collection, testing workflows, and diagnostic algorithms — Domnich & Pariani, Expert review of molecular diagnostics (paywalled)
- saliva
- self-collection
2026
Among 101 working-age women in Chicago, 70% returned at-home kits for capillary blood and saliva collection, demonstrating that patient-centric microsampling of stress biomarkers (cortisol and CRP) is feasible in diverse urban populations. This supports decentralised diagnostics for population health research.
A feasibility study exploring precarious employment and stress-related health among women — Oddo et al., BMC public health
- blood
- saliva
- capillary
- self-collection
- cortisol
- biomarkers
2026
The study found that coached dried blood spot collection was feasible for remote biobehavioural assessment of CTRA gene expression among Black women activists, with usable data from 28 of 29 participants at baseline and 27 at follow-up. Within-person increases in activist identity and search for meaning were associated with more favourable CTRA gene expression changes, though mean CTRA did not shift across the group over the two-month period.
The paradox of action: Trajectories in distress, meaning, and gene regulation following self-directed activist engagement among Black women — Geyton & Cole, SSM. Mental health
- blood
- dried
- dbs
- self-collection
- dct
2026
Self-collected dried blood spots from 40 healthy participants arrived intact and yielded good-quality DNA, with most immune and epigenetic biomarkers remaining stable for up to six weeks at room temperature. The study confirms that minimally invasive dried blood and plasma spot sampling is feasible for scalable, longitudinal biomolecular surveillance in occupational health settings.
Dried blood spot-based monitoring of immune and epigenetic biomarkers in occupational exposure studies — De Ryck et al., Journal of exposure science & environmental epidemiology (paywalled)
- blood
- dried
- dbs
- self-collection
- validation
- acceptability
- biomarkers
2026
Finger-stick dried blood spots produce creatinine measurements that correlate strongly with venous plasma (R² = 0.97), with 91% sensitivity and 96% specificity for detecting reduced eGFR. Creatinine stays stable in dried spots for up to one month at refrigerated or frozen temperatures, supporting accurate home-based kidney function screening, patient follow-up, and medication management.
Creatinine measurement from finger stick dried blood spots with a routine chemistry analyzer for estimation of GFR — van Dam et al., Clinical chemistry and laboratory medicine (paywalled)
- blood
- dried
- capillary
- dbs
- self-collection
- validation
- venous-agreement
- haematocrit
2026
This study demonstrated that a fully remote genome sequencing study using self-collected dried blood spots and buccal swabs is feasible for individuals with Prader-Willi syndrome, with all participants completing the study and reporting the process was easy despite being lengthy. The design successfully returned actionable genetic findings, including those related to blood clot formation, to participants.
Study design with responsible return of results for a fully remote genome sequencing study in individuals with Prader-Willi syndrome — Vrana-Diaz et al., Genetics in medicine open
- blood
- saliva
- dried
- dbs
- self-collection
- acceptability
- dct
- genotyping
2026
This scoping review identified 15 distinct technologies for measuring HbA1c from capillary blood, with point-of-care devices requiring only 2 to 10 µL and delivering results within minutes. However, diagnostic accuracy varied widely between studies and devices, and most evidence comes from high-income countries, indicating gaps in validation for low- and middle-income settings where decentralised screening is most needed.
HbA1c measurement using capillary blood in epidemiological studies: a scoping review of technologies and approaches — Breternitz et al., BMC endocrine disorders (paywalled)
- blood
- dried
- capillary
- dbs
- self-collection
- validation
2026
Home DBS sampling gave testosterone results that agreed well with venous blood in men on intramuscular testosterone undecanoate, but showed falsely high values in those using topical gel, likely from skin contamination. Patients preferred home collection for its convenience, suggesting DBS is viable for decentralised monitoring of injectable testosterone if patients are taught proper technique.
From venipuncture to self-sampling dried blood spots: a shift in monitoring testosterone levels — Olthof et al., Clinical chemistry and laboratory medicine (paywalled)
- blood
- dried
- capillary
- dbs
- self-collection
- validation
- venous-agreement
- acceptability
- fertility
- hormones
- tdm
2026
This narrative review surveys remote biospecimen collection products for sexual health research, including dried blood spots and volumetric absorptive microsampling, and concludes that successful implementation needs a multidisciplinary, participant-centred team with sufficient time allocated to the complexities of collection procedures and processes.
A Narrative Review of Remote Biospecimen Collection Product and Implementation Considerations for Sexual Health Clinical Research — Horvath et al., AIDS and behavior (paywalled)
- blood
- dried
- vams
- dbs
- self-collection
- validation
- dct
- serology
- sti
2025
Worked case studies of patient-centric sampling deployed in pharmaceutical drug development: how sponsors have implemented it, rather than whether it is possible.
Case Studies on the Use of Patient-centric Sampling for Clinical Studies in Pharmaceutical Drug Development — Patel et al., The AAPS Journal (paywalled)
- dct
- venous-agreement
- blood
- self-collection
- pediatric
- validation
- biomarkers
2025
A phase 1 trial designed around participant self-collection of pharmacokinetic samples at home, with video training and pre-assembled kits: evidence that the model is a training and logistics package, not only a device.
At-Home Self-Collection of Pharmacokinetic Data: Design and Results From a Phase 1 Open-Label Feasibility Trial — Raoufinia et al., Clinical Pharmacology in Drug Development
- dct
- neoteryx-mitra
- blood
- tdm
- self-collection
- dried
2025
A systematic review found mixed economic evidence for microsampling in therapeutic drug monitoring; one study reported no cost reduction with DBS home-sampling, €688 versus €676, whilst another predicted savings up to 61%. The authors caution that more work is required to assess costs alongside clinical outcomes and optimise logistics for decentralised implementation.
The economic evidence for microsampling to support therapeutic drug monitoring: A systematic review — Carland et al., British Journal of Clinical Pharmacology (paywalled)
- vams
- blood
- economics
- dbs
- tdm
- self-collection
- dried
- antimicrobials
- pediatric
- immunosuppressants
- validation
2025
A review of 39 studies found that dried blood spot and volumetric absorptive microsampling show promising results for therapeutic drug monitoring of oral targeted anticancer drugs. The authors state that external validation remains crucial to confirm reliability, citing haematocrit effects and sample stability as key challenges.
Advancing Therapeutic Drug Monitoring for Oral Targeted Anticancer Drugs: From Hospital-Based Towards Home-Sampling — Meertens et al., Biomedical Chromatography
- vams
- blood
- dbs
- tdm
- self-collection
- haematocrit
- dried
- oncology
- validation
2025
A UK survey of 2,816 healthcare workers found that 74% preferred at-home PCR testing and 52% preferred at-home serological sampling over hospital visits; some reported blood-collection or kit difficulties, and the authors conclude that home sampling is acceptable and workable for keeping participants in long-running studies.
Comparing Participant Experiences of at-Home and Hospital-Based Biological Sampling: Cross-Sectional Insights From the SIREN Study — Lut et al., Health Science Reports
- acceptability
- blood
- self-collection
- serology
- capillary
2025
An evaluation of blood sampling strategies across a large UK healthcare-worker cohort study, covering how sampling approach affected participation.
Evaluating blood sampling strategies within the SIREN study: the experience from a large cohort of healthcare workers in the UK — Hettiarachchi et al., BMC Medical Research Methodology
- dct
- acceptability
- blood
- economics
- self-collection
- capillary
- validation
2025
Plasma lipidomes from self-collected upper-arm capillary blood were statistically indistinguishable from paired venous plasma, most classes at r=0.95–0.99, validating at-home capillary self-collection for lipidomics.
Comparison of capillary and venous plasma lipidomes: validation of self-collected blood for plasma lipidomics — Hameed et al., J. Lipid Research
- venous-agreement
- blood
- self-collection
- capillary
- liquid
- validation
- biomarkers
2025
Taxonomic and diversity profiles differed between unstabilised swabs and stabilised OmniGene kits, with transport time disproportionately affecting swab samples; the collection method had a greater impact on taxa and diversity than transport time, highlighting the need for standardised stool collection in decentralised microbiome studies.
Stabilized and unstabilized sampling methods result in differential fecal 16S rRNA microbial sequencing results — Stamper et al., PloS one
- stabilised
- dna-genotek-omnigene
- self-collection
- microbiome
- stool
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