The Library
1530 papers on microsampling and monitoring, each with a finding paraphrased to our standard and labelled in one vocabulary. Every entry links to a legitimate copy; nothing is copied from an abstract.
Papers 1–100 of 280 labelled “acceptability”, newest first.
2026
Participants preferred the Omnigene and Zymo oral swabs for comfort and ease of use, whilst the Omnigene device yielded the highest median bacterial DNA concentration compared to the other devices. The results indicate that the choice of self-collection device impacts both patient acceptability and DNA yield for oral microbiome analysis.
Comparison of self-collected oral swabs for supragingival microbiome characterization using 16S rRNA gene amplicon sequencing — Rooney et al., Journal of microbiological methods (paywalled)
- acceptability
- stabilised
- self-collection
- microbiome
- saliva
2026
A study of 2500 women found 99.0% agreement between first-void urine and vaginal self-sampling for HPV detection using Cobas4800, with 98.1% of participants preferring urine. Although conducted in a resource-limited setting which may limit generalisability, these results support urine as a viable sample type for decentralised, patient-centric screening.
Comparative efficacy, feasibility and acceptability of HPV DNA testing on first-void urine versus self-collected vaginal samples: a real-world study in a resource-limited setting — Bose et al., BMJ global health
- urine
- first-void
- self-collection
- acceptability
- hpv
- sti
2026
First-void urine and self-collected vaginal swabs showed similar sensitivity and specificity to clinician-collected cervical samples for high-risk HPV detection across two real-time PCR assays, supporting their use as decentralised, patient-collected alternatives; most women preferred first-void urine for regular cervical screening.
Comparative performance of first-void urine and self-collected vaginal swabs against clinician-collected cervical samples using 2 HPV real-time assays in Indian women — A et al., Journal of gynecologic oncology (paywalled)
- acceptability
- first-void
- sti
- self-collection
- hpv
- urine
2026
This randomised sub-study found return rates of 10.4% for Colli-Pee, 10.1% for FLOQSwabs and 7.4% for Evalyn-Brush. All devices yielded sufficient DNA with low invalid rates, but the authors noted the study was limited by low overall participation.
Comparison of three different hpv self-sampling tools - a subanalysis of the prospective, randomized hannover self-collection study — Hempel et al., Archives of gynecology and obstetrics
- urine
- first-void
- colli-pee
- self-collection
- acceptability
- hpv
- sti
2026
At-home volumetric absorptive microsampling (VAMS) for anti-seizure medicines was feasible and reliable, with strong correlations to clinic VAMS and low bias for lacosamide, lamotrigine and levetiracetam; quantitative dried blood spot (qDBS) was a reliable alternative in the ambulatory setting, though older age reduced sampling quality.
Real-world evaluation of capillary microsampling for drug monitoring of anti-seizure medications — Cancellerini et al., Epilepsia (paywalled)
- vams
- venous-agreement
- acceptability
- blood
- qdbs
- tdm
- self-collection
- dried
- capillary
2026
This review found that volumetric microsampling devices, such as Mitra, HemaPEN, HemaXis DB10, and Tasso-M20, overcome haematocrit bias, whilst Telimmune plasma separation cards enable direct plasma collection without centrifugation. These technologies support patient-centric, decentralised sampling, though the authors note that clinical validation remains limited across different drugs and patient populations.
A Review of Blood-Based Microsampling Devices for Patient-Centered Application in Therapeutic Drug Monitoring — Huhn & Scherf-Clavel, Therapeutic drug monitoring (paywalled)
- vams
- volumetric
- acceptability
- neoteryx-mitra
- blood
- dbs
- tdm
- self-collection
- haematocrit
- dried
- capillary
- validation
2026
The study found that although participants preferred patient-centric microsampling devices for home use, the agreement with venous plasma for measuring CRP and cytokines was inconsistent, indicating that further validation is required before these methods replace standard venipuncture.
Limited agreement of cytokines and CRP through patient-centric microsampling compared to venipuncture in healthy adults — Tuttle et al., Bioanalysis (paywalled)
- dct
- venous-agreement
- acceptability
- blood
- dbs
- self-collection
- dried
- biomarkers
2026
This pilot study found that mailing self-collection kits to endometrial cancer survivors was feasible and acceptable, whilst also observing that chemotherapy or radiation reduced beneficial vaginal bacteria compared to surgery alone.
Stool and vaginal microbiome profiles patterns among Black and White endometrial cancer survivors: A pilot study in North Carolina — Jin et al., PloS one
- stool
- self-collection
- acceptability
- microbiome
2026
Self-sampling for HPV testing using urine and swab devices achieved high DNA detection rates, 92.1-99.7%, and very high participant acceptance, 99.1%, in a primary care population, supporting decentralised screening in low-resource settings.
Population-based self-sampling under primary care conditions - a possible approach for cervical cancer screening in Indonesia (IndoCerCa study) — Wenang et al., Reproductive health
- urine
- self-collection
- validation
- acceptability
- hpv
- sti
2026
Community pharmacy-based testing and treatment for chlamydia and gonorrhoea using self-collected first-catch urine was highly acceptable to users and successfully identified new cases, with pharmacists efficiently prescribing antibiotic treatment. This supports decentralised sampling by showing that asymptomatic STI testing can be delivered through self-collection in non-clinical settings with good uptake and patient satisfaction.
Implementation of community pharmacy-based testing and treatment for Chlamydia trachomatis and Neisseria gonorrhoeae in Nova Scotia (Swab-Rx study) — d'Entremont-Harris et al., Journal of the American Pharmacists Association : JAPhA (paywalled)
- urine
- first-void
- self-collection
- acceptability
- sti
2026
This meta-analysis found that urine self-sampling for HPV detection had significantly lower sensitivity for high-grade lesions compared to vaginal and cervical samples, though specificity remained comparable. Despite the reduced diagnostic accuracy, the non-invasive and acceptable nature of urine sampling supports its use as a decentralised option to improve screening uptake.
A systematic review and meta-analysis of diagnostic accuracy of urine self-sampling for human papillomavirus detection in cervical cancer screening — Nath et al., Journal of medical screening (paywalled)
- acceptability
- sti
- self-collection
- hpv
- urine
- validation
2026
Self-collected HPV testing was highly acceptable to transgender men with a cervix, and most participants preferred urine-based self-sampling over vaginal sampling, suggesting urine self-collection could help overcome barriers to cervical screening in this group.
Genital human papillomavirus detection in self-samples from transgender men — Vervalcke et al., European journal of obstetrics, gynecology, and reproductive biology (paywalled)
- urine
- self-collection
- acceptability
- hpv
- sti
2026
The study determined that an at-home saliva collection protocol using the passive drool method was feasible for Black women with histories of abuse, with 84% of participants completing at least one full day of adherent sampling. While the decentralised approach yielded usable cortisol data, women with histories of forced sex exposure showed lower protocol adherence scores.
Repeat At-Home Saliva Collection to Measure Cortisol Awakening Response (CAR): Protocol Feasibility Study Among Black Women With Histories of Abuse — Tsuyuki et al., Interactive journal of medical research (paywalled)
- dct
- acceptability
- cortisol
- self-collection
- liquid
- saliva
2026
This proof-of-concept study demonstrated that patients with inflammatory bowel disease could successfully perform capillary blood microsampling at home with high analytical success rates, and a majority preferred this decentralised approach over hospital venous draws.
Implementation of a Capillary Blood Self-Sampling Technique at Home for Monitoring of Patients With IBD — Schuurman et al., Inflammatory bowel diseases
- acceptability
- multimodal
- blood
- rpm
- self-collection
- capillary
- liquid
2026
In a 20-person proof-of-concept pilot among veterans with HIV, remote self-collection of dried blood spots for phosphatidylethanol monitoring was feasible and acceptable, with high return and analysis rates and positive feedback; a small first step toward decentralised alcohol biomarker monitoring rather than proof of it.
Remote alcohol biomarker monitoring to promote drinking reductions among people with HIV: A proof-of-concept pilot study — Sheinfil et al., Journal of substance use and addiction treatment (paywalled)
- acceptability
- blood
- dbs
- self-collection
- dried
- biomarkers
2026
In a pilot mixed-methods study of youth with HIV, mailed HemaSpot-HF kits enabled home-based dried blood spot collection that participants found feasible and acceptable, supporting remote viral load monitoring and a self-management model for decentralised care.
An Examination of Perceptions and Usage of Dried Blood Spot Biosampling Technology for HIV Viral Load Collection Among Youth with HIV — Gurung et al., AIDS and behavior (paywalled)
- blood
- dried
- dbs
- self-collection
- acceptability
- dct
- serology
2026
The study found that quantitative dried blood spot sampling provided high clinical agreement for tacrolimus and creatinine monitoring, with patients rating the self-collection devices as user-friendly. These results support the feasibility of decentralised therapeutic drug monitoring for immunosuppressants.
Patient-centric capillary dried blood spot sampling for tacrolimus and creatinine monitoring in clinical practice — De Baets et al., Clinical chemistry and laboratory medicine (paywalled)
- blood
- dried
- capillary
- dbs
- qdbs
- self-collection
- venous-agreement
- acceptability
- tdm
- immunosuppressants
2026
This pilot study demonstrated that a fully remote web-based testing programme for sexually transmitted and blood-borne infections was feasible and acceptable overall, although participants encountered specific collection challenges with the dried blood spot component.
Comprehensive at-home sexually transmitted and blood borne infection (STBBI) testing program: A pilot study — Christensen et al., International journal of STD & AIDS
- blood
- urine
- dried
- dbs
- self-collection
- acceptability
- sti
2026
The study found that oral fluid microsampling using VAMS has high patient acceptability, 90% vs 28% for urine, and over 88% agreement with urine toxicology screening, making it a practical alternative for substance use disorder monitoring with reduced sample adulteration risk and lower costs.
Evaluation of oral fluid microsampling as a urine surrogate matrix in substance use disorder care: clinical applicability and analytical performance — Thiebot et al., Clinical toxicology (paywalled)
- vams
- acceptability
- toxicology
- urine
- saliva
2026
Task sharing dried blood spot collection for HIV viral load testing with community lay cadres achieved high diagnostic agreement with healthcare worker collections and was highly acceptable to patients. This approach offers a viable strategy to overcome healthcare worker shortages and support decentralised viral load monitoring in resource-limited settings.
Feasibility and acceptability of task sharing collection of HIV viral load dried blood spot samples with community lay cadres: A cross-sectional diagnostic validation study in Zimbabwe — Prust et al., PLOS global public health
- acceptability
- blood
- dbs
- dried
- serology
- validation
2026
This study found that home-based multi-pathogen self-sampling, including urine collection, was feasible and highly acceptable to women in Zambia, with the majority preferring home visits over clinic attendance.
Acceptability and feasibility of one-stop home-based genital self-sampling for female genital schistosomiasis, human papilloma virus and self-testing for trichomonas and HIV: the Zipime Weka Schista study in Zambia — Ndubani et al., BMC women's health (paywalled)
- urine
- self-collection
- acceptability
- hpv
- sti
2026
This review establishes that microsampling across blood, saliva, urine and stool matrices offers validated workflows and regulatory recognition for human biomonitoring comparable to conventional methods. It finds that these decentralised approaches enhance participant acceptability and enable screening in remote or low-resource settings.
Integrating Microsampling in Human Biomonitoring: Methodologies, Regulatory Frameworks, and Case Study Insights — Rajamani & Poongavanam, Critical reviews in analytical chemistry (paywalled)
- wearable
- acceptability
- multimodal
- sweat
- blood
- dbs
- standards
- dried
- serology
- colorectal
- pediatric
- stool
- urine
- validation
- saliva
- biomarkers
2026
Volumetric microsampling can enable patient-centred therapeutic drug monitoring with high patient preference and acceptable method validation for many drugs, but conversion from capillary to plasma and agreement with venous sampling varies by analyte and requires careful validation.
Volumetric Microsampling for Patient-Centric Therapeutic Drug Monitoring in Clinical Pharmacology: A Scoping Review — Tummala et al., Journal of clinical pharmacology (paywalled)
- volumetric
- venous-agreement
- acceptability
- blood
- tdm
- self-collection
- haematocrit
- dried
- capillary
- validation
2026
Capillary fingerstick sampling showed high correlation and agreement with venous sampling for serum AMH but with proportional bias, so it may improve access to testing yet should not be considered fully interchangeable without further validation.
Comparison of serum anti-Müllerian hormone concentrations measured in capillary fingerstick and venous samples from Korean reproductive-aged women — Lavadia et al., Clinical and experimental reproductive medicine (paywalled)
- blood
- capillary
- validation
- venous-agreement
- acceptability
- fertility
- hormones
2026
Capillary blood collected with Tasso+ devices demonstrated strong agreement with venous blood for primary Athlete Biological Passport markers (haemoglobin, reticulocytes, OFF-score, ABPS) with correlations ≥0.9, though platelet count showed poor concordance. Despite 44 of 209 samples failing pre-analytical checks mainly due to coagulation, high athlete acceptance and minimal pain support capillary sampling as a less invasive, viable alternative for decentralised anti-doping controls.
Capillary Blood as a Potential New Matrix for the Athlete Biological Passport: A Field-Based Comparison Study — Requena-Tutusaus et al., Medicine and science in sports and exercise (paywalled)
- blood
- liquid
- capillary
- validation
- venous-agreement
- acceptability
- doping
2026
In a cohort of 62 participants evaluating home self-collection with the TassoPlus device, 38 returned samples, with 29% excluded due to insufficient plasma volume below 200 ΔL. Although viral load measurements in adequate samples correlated well with conventional testing (r = 0.800), the high failure rate and missed detection in low-volume viremic samples indicate that further technical refinements are necessary before clinical adoption.
Feasibility and reliability of decentralized HIV-1 viral load monitoring on self-sampled blood — Mendes de Leon et al., PloS one
- blood
- liquid
- capillary
- self-collection
- validation
- venous-agreement
- acceptability
- serology
2026
In a feasibility randomised controlled trial with 28 adults aged 65 years, 62% successfully self-collected finger-prick capillary blood samples for influenza antibody and vitamin D measurement. While overall study procedures were acceptable, the capillary sampling method requires refinement before wider deployment in decentralised diagnostics for older adults.
PROTECTIVE-D-a feasibility randomised controlled trial examining the effect of a positive mood intervention and vitamin D supplementation on the immunological responses to influenza vaccination in older adults — Royal et al., Pilot and feasibility studies (paywalled)
- blood
- capillary
- self-collection
- acceptability
- dct
2026
Postnatal women view the six-week check-up as a window of opportunity for cervical screening via urine self-sampling, though some feel it may be too soon after delivery. The study reveals women's health is perceived as neglected compared with infant care, supporting feasibility of a trial to test early postnatal screening uptake.
Investigating the Acceptability of Cervical Screening and Self-Sampling in Postnatal Women at the 6-Week Postnatal Check-Up: A Qualitative Study — Newhouse et al., Health expectations : an international journal of public participation in health care and health policy
- urine
- self-collection
- acceptability
- hpv
2026
Among 454 postnatal women, 74.4 per cent would be more likely to undergo cervical screening if offered urine self-sampling for HPV at six weeks postnatal, and 54 per cent preferred this method to conventional clinician-taken samples. This indicates high acceptability of patient-collected urine for decentralised HPV screening in the postnatal period, which could improve uptake when integrated into routine postnatal care.
Investigating the acceptability of cervical screening, using conventional clinician-taken cervical samples or urine self-sampling, at 6 weeks postnatal: A cross-sectional questionnaire — Cullimore et al., Journal of medical screening
- urine
- self-collection
- acceptability
- hpv
2026
Dried blood spot collection proved feasible during parabolic flight, with seventeen of twenty volunteers successfully providing samples for caffeine pharmacokinetic profiling. The method yielded stable metabolic ratios between ground and weightless conditions, and participants reported high satisfaction, suggesting DBS could support therapeutic drug monitoring in remote or extreme environments such as long-term spaceflight.
Feasibility of dried blood spot collection for caffeine pharmacokinetic studies in microgravity: Insights from parabolic flight campaigns — Derobertmasure et al., British journal of clinical pharmacology
- blood
- dried
- dbs
- self-collection
- acceptability
- tdm
- genotyping
2026
A paired-sample study of postnatal cervical screening proved feasible with high attendance and low test inadequacy. Urine self-sampling for HPV showed lower sensitivity (60% at six weeks) than clinician-taken samples, suggesting it may be less reliable in this population.
Comparison of Cervical Screening at 6- and 12-Weeks Postnatal: A Paired-Sample Feasibility Study — Cullimore et al., BJOG : an international journal of obstetrics and gynaecology (paywalled)
- urine
- self-collection
- acceptability
- hpv
- sti
2026
Self-collected dried blood spots from 40 healthy participants arrived intact and yielded good-quality DNA, with most immune and epigenetic biomarkers remaining stable for up to six weeks at room temperature. The study confirms that minimally invasive dried blood and plasma spot sampling is feasible for scalable, longitudinal biomolecular surveillance in occupational health settings.
Dried blood spot-based monitoring of immune and epigenetic biomarkers in occupational exposure studies — De Ryck et al., Journal of exposure science & environmental epidemiology (paywalled)
- blood
- dried
- dbs
- self-collection
- validation
- acceptability
- biomarkers
2026
This study demonstrated that a fully remote genome sequencing study using self-collected dried blood spots and buccal swabs is feasible for individuals with Prader-Willi syndrome, with all participants completing the study and reporting the process was easy despite being lengthy. The design successfully returned actionable genetic findings, including those related to blood clot formation, to participants.
Study design with responsible return of results for a fully remote genome sequencing study in individuals with Prader-Willi syndrome — Vrana-Diaz et al., Genetics in medicine open
- blood
- saliva
- dried
- dbs
- self-collection
- acceptability
- dct
- genotyping
2026
Home DBS sampling gave testosterone results that agreed well with venous blood in men on intramuscular testosterone undecanoate, but showed falsely high values in those using topical gel, likely from skin contamination. Patients preferred home collection for its convenience, suggesting DBS is viable for decentralised monitoring of injectable testosterone if patients are taught proper technique.
From venipuncture to self-sampling dried blood spots: a shift in monitoring testosterone levels — Olthof et al., Clinical chemistry and laboratory medicine (paywalled)
- blood
- dried
- capillary
- dbs
- self-collection
- validation
- venous-agreement
- acceptability
- fertility
- hormones
- tdm
2025
A UK survey of 2,816 healthcare workers found that 74% preferred at-home PCR testing and 52% preferred at-home serological sampling over hospital visits; some reported blood-collection or kit difficulties, and the authors conclude that home sampling is acceptable and workable for keeping participants in long-running studies.
Comparing Participant Experiences of at-Home and Hospital-Based Biological Sampling: Cross-Sectional Insights From the SIREN Study — Lut et al., Health Science Reports
- acceptability
- blood
- self-collection
- serology
- capillary
2025
An evaluation of blood sampling strategies across a large UK healthcare-worker cohort study, covering how sampling approach affected participation.
Evaluating blood sampling strategies within the SIREN study: the experience from a large cohort of healthcare workers in the UK — Hettiarachchi et al., BMC Medical Research Methodology
- dct
- acceptability
- blood
- economics
- self-collection
- capillary
- validation
2025
A head-to-head of four upper-arm capillary devices, including TAP Micro Select, versus fingerstick and venous: experience and performance varied by device with none clearly superior, while analyte correlations with venous were similar across all.
Comparing capillary blood collection technologies: patient experience, device performance and clinical accuracy — Collier et al., Bioanalysis (paywalled)
- blood
- liquid
- yourbio
- capillary
- venous-agreement
- acceptability
- validation
- bd-microtainer
2025
A vacuum-assisted upper-arm device collected a mean 538 µL and met the volume target in 85.5% of cases; 17 of 19 analytes met CLIA agreement with venous, with pain lower than fingerstick.
Evaluation of a Simplified Upper-Arm Device for Vacuum-Assisted Collection of Capillary Blood — Schaff et al., Diagnostics
- blood
- liquid
- capillary
- venous-agreement
- acceptability
- validation
- bd-microtainer
2025
In 498 women living with HIV, self-collected first-void urine and vaginal samples showed 78% high-risk HPV prevalence and good genotype concordance, kappa 0.64-0.78. Participants preferred the Colli-Pee device over the Evalyn Brush, supporting decentralised, patient-centric screening feasibility.
Feasibility of First-Void Urinary and Vaginal Self-Sampling for High-Risk Human Papillomavirus Testing Among Women Living With Human Immunodeficiency Virus in Guinea-Bissau-A Multicenter Cross-Sectional Study — Madsen et al., Journal of medical virology
- colli-pee
- acceptability
- first-void
- sti
- self-collection
- hpv
- urine
2025
This study compared four dried blood spot devices for glucocorticoid detection, finding that the Mitra VAMS device offered the best combination of analytical recovery and user usability, whilst the HemaXis DB10 showed the least bias compared to whole blood.
Analytical and usability comparison of microsampling dried blood spot devices for glucocorticoid detection in sports using ultra-high-performance liquid chromatography-tandem mass spectrometry — Chen et al., Analytica chimica acta (paywalled)
- vams
- acceptability
- neoteryx-mitra
- doping
- blood
- dbs
- haematocrit
- dried
- toxicology
- hormones
- validation
2025
The study determined that using self-collected dried blood spots alongside online surveys was a feasible and acceptable method for remote pre-exposure prophylaxis adherence monitoring, with 64% of participants returning at least one blood specimen.
Remote pre-exposure prophylaxis adherence monitoring among young, Black men who have sex with men: a feasibility and acceptability pilot study — Jones et al., Current psychology (paywalled)
- dct
- acceptability
- blood
- dbs
- tdm
- self-collection
- dried
2025
A comparison of three patient-centric dried blood microsampling devices, paper DBS, Mitra and Tasso-M20, found strong to excellent correlation with traditional venous plasma for measuring branched-chain amino acids and ketoacids. Participants reported high acceptability and expressed a strong willingness to use these devices for decentralised self-collection.
Quantitation of BCAA and BCKA in plasma and patient-centric dried blood microsamples in a clinical setting — Tierney et al., Bioanalysis
- vams
- venous-agreement
- acceptability
- neoteryx-mitra
- blood
- dbs
- metabolome
- dried
- validation
- biomarkers
2025
In a one-week virtual home clinic with 134 participants, 86 per cent returned saliva and 84 per cent returned stool, and most components were feasible and acceptable despite device and logistical challenges. This supports decentralised, patient-centric self-collection of non-blood biospecimens for research.
Collecting at-Home Biometric Measures for Longitudinal Research From the i3C: Feasibility and Acceptability Study — Russell et al., JMIR human factors
- saliva
- stool
- self-collection
- acceptability
- dct
- microbiome
2025
While 72 per cent of participants returned self-collected dried blood spot kits, only 46 per cent provided samples adequate for a full cardiometabolic profile, with insufficient blood volume cited as the primary difficulty.
Feasibility of self-administered dried blood spot collection for cardiometabolic profile analysis in a population-based sample of young adults — Livingstone et al., PloS one
- blood
- dried
- dbs
- self-collection
- acceptability
- biomarkers
2025
Urine self-sampling for HPV showed non-inferior specificity to cervical samples, 85.19%, and found 96% of high-grade lesions. While acceptable, a survey of 1382 participants found 41.6% preferred conventional screening, showing the importance of offering choice in a decentralised, patient-centric programme.
Urine human papillomavirus testing for cervical screening in a UK general screening population: a diagnostic test accuracy study — Davies et al., The British journal of general practice : the journal of the Royal College of General Practitioners
- urine
- first-void
- colli-pee
- self-collection
- acceptability
- hpv
- sti
2025
A study of 100 Brazilian women with high-grade cervical lesions found excellent concordance for high-risk HPV detection between clinician-collected samples and patient-centric, self-collected vaginal or first-void urine samples. Self-sampling was preferred for comfort, though the study's single-centre setting may limit generalisability.
Self-sampling for HPV genotyping: a study of vaginal and urine collection in Brazilian women with high-grade lesions — Castanheira et al., Clinics
- acceptability
- first-void
- sti
- self-collection
- hpv
- urine
- genotyping
2025
A study of older rural US patients found that 96 to 98 per cent of self-collected dried blood spot specimens were successfully analysed for HIV viral load, with high acceptability. However, concordance between self-reported and measured viral load was only 69 to 82 per cent, highlighting the value of objective decentralised microsampling over self-reporting.
Acceptability and Feasibility of Self-Collected Dried Blood Spot Specimens for Viral Load Monitoring among Rural Older People Living with HIV — Walsh et al., AIDS and behavior (paywalled)
- dct
- acceptability
- blood
- dbs
- self-collection
- dried
- serology
2025
In a Belgian colposcopy referral cohort, a study found that 66.6% of women preferred home-based first-void urine self-sampling over physician-taken samples, and 96.6% found the Colli-Pee UCM FV-5010 device easy to use. This supports patient-centric, decentralised screening, though results are limited to this specific referral population.
Home-based urinary HPV self-sampling for the detection of cervical cancer precursor lesions: attitudes and preferences from Belgian females participating in the CASUS study — Hendrickx et al., Archives of public health = Archives belges de sante publique
- colli-pee
- acceptability
- first-void
- self-collection
- hpv
- liquid-biopsy
- liquid
- urine
2025
This study found that 80% of Middle Eastern-North African women preferred urine HPV self-sampling over clinician-directed screening, and 73% favoured home collection. 80% reported this decentralised method would positively impact future screening intent.
Acceptability of Home-Based Urine Self-Collection for Cervical Cancer Screening Among Women Receiving Care at the Arab Community Center for Economic and Social Services in Michigan — Guetterman et al., Cancer medicine
- urine
- self-collection
- acceptability
- hpv
2025
The Egoo Phe system showed strong concordance with dried blood spot testing across 100 paired samples, with median phenylalanine 274 versus 270 μmol/L and readings a mean 4.6% higher, and high caregiver acceptance; the small sample size limits generalisability and further validation in larger cohorts is required.
Point-of-Care Testing in PKU: A New ERA of Blood Phenylalanine Monitoring — Pinto et al., Nutrients
- acceptability
- blood
- dbs
- self-collection
- pediatric
- validation
2025
This study established conversion methods for estimating plasma concentrations from whole blood VAMS samples for seven out of ten oral anticancer drugs, finding good agreement between capillary and venous samples. Patients reported a positive experience with home sampling using this microsampling technique.
Clinical Application of Volumetric Absorptive Microsampling for Therapeutic Drug Monitoring of Oral Targeted Anticancer Drugs — Meertens et al., Therapeutic drug monitoring
- vams
- venous-agreement
- acceptability
- blood
- tdm
- self-collection
- oncology
- capillary
- validation
2025
This meta-analysis found strong agreement between self-collected capillary blood and venous samples for laboratory results. Capillary sampling was associated with significantly lower pain scores than venipuncture, particularly when using upper arm devices rather than fingerprick methods.
Comparison of laboratory results and pain perception in self-sampled capillary blood versus venous blood sampling: a systematic review and meta-analysis — Schröder et al., Clinical biochemistry (paywalled)
- venous-agreement
- acceptability
- blood
- self-collection
- capillary
- liquid
- validation
2025
An online self-sampling intervention for chlamydia and gonorrhoea using urine kits achieved a 20.7% positivity rate, with 90% of infections being extragenital, and linked 81% of positive cases to treatment, indicating high acceptability and feasibility for decentralised STI testing.
TESTATE STI project: an online chlamydia and gonorrhoea self-sampling strategy for gay, bisexual and other men who have sex with men and trans people in Catalonia (Spain) — Martínez-Riveros et al., Sexually transmitted infections (paywalled)
- acceptability
- sti
- self-collection
- liquid
- urine
2025
This survey found that whilst consumers were optimistic about using saliva for periodontitis diagnosis, many clinicians remained uncertain about the accuracy of the method. The results indicate a need for further evidence and education to support the adoption of decentralised saliva sampling workflows.
A survey of Australian consumers' and dentists' perceptions of saliva as a biofluid for periodontitis diagnosis — Sun et al., BMC oral health
- saliva
- self-collection
- acceptability
2025
Capillary blood self-collected with the VAMS device showed 100 per cent agreement with serum for detecting SARS-CoV-2 S RBD antibodies in participants with known past infection, and saliva showed slightly lower but high agreement; agreement was good to almost perfect in those without known antibodies, and most participants found finger prick easy while half found the microsampler easy, supporting decentralised serosurveillance.
Performance and feasibility of self-microsampling of capillary blood and saliva for serological testing of SARS-CoV-2 — Morales et al., PloS one
- vams
- venous-agreement
- acceptability
- blood
- self-collection
- serology
- capillary
- saliva
2025
Self-collected capillary samples showed good agreement with venous samples for most safety monitoring parameters in patients with rheumatic disease, although platelet counts were less reliable and haemolysis affected some biochemistry results. Patients found the self-sampling process easy and virtually painless, suggesting it is a feasible option for decentralised monitoring.
Self-sampling of capillary blood for safety monitoring of DMARD therapy in patients with rheumatic disease: a feasibility and method-comparison study — Adelhelm et al., Scandinavian journal of clinical and laboratory investigation (paywalled)
- venous-agreement
- acceptability
- blood
- self-collection
- capillary
- liquid
2025
The True Dose kit achieved a high System Usability Scale score of 82.7 and enabled 92% of participants to collect the required capillary blood volume, with a median sampling time of 10.42 minutes, indicating good usability but highlighting the need for clearer instructions and stress management to support reliable decentralised sampling.
Capillary Blood Self-Sampling for Therapeutic Drug Monitoring: A Mixed-Methods Usability Study of the True Dose<sup>®</sup> Kit — Crafoord et al., BioMed research international
- blood
- capillary
- self-collection
- acceptability
- tdm
2025
This study describes the iterative development of a novel capillary self-sampling device, demonstrating that the fourth prototype enabled 77.5% of users to successfully collect at least 500 µL of blood with high usability and acceptability scores.
The development of a novel device to aid in capillary macro blood self-sampling via an iterative study design — Herrijgers et al., Expert review of medical devices (paywalled)
- blood
- capillary
- self-collection
- acceptability
2025
Healthcare professionals considered a postal self-collection service for diabetes review acceptable, anticipating it would reduce missed appointments and enable more holistic use of consultation time, while cautioning that administrative burden and public perception of diminished face-to-face care would need managing. The study indicates that patient-centric microsampling can secure professional support, a prerequisite for decentralised diagnostics.
Healthcare professional views of a diabetes review postal box: A qualitative study — Colley et al., Diabetic medicine : a journal of the British Diabetic Association (paywalled)
- blood
- urine
- self-collection
- acceptability
2025
In 40 participants, dried blood spots showed excellent agreement with venous blood for HBA1c measurement (LCCC 0.982, PCC 0.990, limits of agreement -0.45 to 0.48). The method demonstrated high repeatability (CV 1.13) and clinical conformity (K 0.80), suggesting capillary DBS sampling could replace venipuncture for diabetes monitoring in decentralised settings.
Preliminary comparative study of HBA1c measurement by IEX-HPLC Bio-Rad in dried blood spot vs. whole venous blood — Hadami et al., Annales de biologie clinique (paywalled)
- blood
- dried
- capillary
- dbs
- validation
- venous-agreement
- acceptability
2025
The study found that the Test2Know postal self-sampling service was highly acceptable and usable, with nearly 90% of users willing to reuse or recommend it, and it reached individuals at risk who had not previously tested for HIV or STIs. This supports the role of decentralised, patient-centric microsampling in expanding access to sexual health testing.
Acceptability, usability, and user experiences of an online postal self-sampling approach for HIV and STI testing in Belgium: Test2Know — De Baetselier et al., International journal of STD & AIDS (paywalled)
- self-collection
- acceptability
- serology
- sti
2025
A survey of 146 Brazilian infertility patients found that 88.3% were willing to perform ultrasounds at home provided image quality and diagnostic accuracy matched clinic-based examinations, and identified patients already familiar with assisted reproductive technology processes as the most suitable candidates for remote fertility monitoring.
Remote fertility care: Are patients prepared to forego physician proximity in favor of accessibility? — Collado et al., JBRA assisted reproduction
- acceptability
- fertility
- rpm
2025
A randomised trial of 47 participants using a mobile app integrated with remote patient monitoring devices achieved a 74% biomarker submission rate over four weeks, with system usability scores of 77–94 and acceptability exceeding benchmarks, showing the platform is feasible for remote data collection in decentralised clinical trials.
Evaluation of a remote biomarker capture system integrated with REDCap: A decentralized randomized trial — Dahne et al., Journal of clinical and translational science
- acceptability
- dct
- rpm
2025
Self-collection of menstrual blood using the M-strip was feasible and highly acceptable to women, and hr-HPV DNA results from menstrual blood showed 100% concordance with direct cervical smears, supporting its potential use in decentralised cervical screening.
HPV-DNA testing from self-sampled menstrual blood using M-strip: A proof-of-concept study on feasibility & acceptance of a novel biosampling method — Chandra et al., The Indian journal of medical research
- blood
- self-collection
- acceptability
- hpv
2025
A home-based PrEP follow-up programme using self-collected specimens and remote monitoring was evaluated among predominantly Black and Latino men who have sex with men in South Florida. Only 37.5% elected home-based care, with completion rates falling from 48.3% at first follow-up to 15% by the third, and most returned to clinic care citing discomfort with self-collection and logistical barriers, highlighting that decentralised HIV prevention requires enhanced support to achieve equitable uptake and persistence.
PrEP Beyond the Clinic: Evaluation of a Home-Based PrEP Follow-Up System Among a Cohort of Predominantly Black and Latino Men who Have Sex with Men in South Florida — Butts et al., Journal of acquired immune deficiency syndromes (paywalled)
- blood
- urine
- self-collection
- acceptability
- sti
2025
Focus groups with 48 women from diverse ethnic groups in Northwest England revealed that self-sampling for cervical screening was highly acceptable, particularly because it offered privacy, autonomy, and reduced discomfort. The study indicates that providing a self-sampling option could increase screening uptake among underserved populations, though participants expressed concerns about test accuracy and practical usability.
Acceptability of Self-Sampling for Cervical Screening in Ethnically Diverse Groups in Northwest England: A Focus Group Study — Whitley et al., Health expectations : an international journal of public participation in health care and health policy
- urine
- self-collection
- acceptability
- hpv
2025
Participants and site personnel viewed the hybrid decentralised trial design favourably, though remote forced vital capacity assessments were more likely to be missed than in-clinic ones, and technological challenges were common.
Participant, site personnel and sponsor perspectives on decentralized trial features in COURAGE-ALS: a randomized clinical trial — Rudnicki et al., Amyotrophic lateral sclerosis & frontotemporal degeneration (paywalled)
- acceptability
- dct
2025
Transgender women in Uganda valued integrated PrEP and STI services that used urine self-collection for therapeutic drug monitoring and infection detection. The convenience of this approach motivated adherence to pre-exposure prophylaxis, while same-day initiation and drug-level feedback supported engagement with care, demonstrating that decentralised, patient-centric models can improve prevention uptake in vulnerable populations.
Integrated PrEP and STI Services for Transgender Women in Uganda: Qualitative Findings from a Randomized Trial — Mujugira et al., AIDS and behavior (paywalled)
- urine
- self-collection
- acceptability
- tdm
- sti
2025
Self-collection of urine and vaginal swabs at home for STI testing in a national survey was feasible and broadly acceptable, with vaginal swabs providing higher testing sensitivity than urine.
Home-based self-collection of biological samples, including vaginal swabs: a mixed methods study for Britain's fourth National Survey of Sexual Attitudes and Lifestyles (Natsal-4) — Oeser et al., Sexually transmitted infections
- urine
- self-collection
- acceptability
- sti
2025
Self-collection of urine, pharyngeal and anal specimens for chlamydia and gonorrhoea testing was highly acceptable among HIV PrEP clients in Vietnam, with 97.9% providing specimens from all three sites and 99.4% willing to repeat the process; cost was the most important factor influencing testing preferences.
Preferences and Acceptability of Testing for Sexually Transmitted Infections in an HIV Pre-Exposure Prophylaxis Clinic in Hanoi, Vietnam — Bui et al., Sexually transmitted diseases (paywalled)
- urine
- self-collection
- acceptability
- sti
2025
In 20 adults, CRP measured in urine and saliva strongly correlated with serum CRP (Spearman rho 0.886) and was significantly elevated in participants with systemic inflammation compared with controls, suggesting these noninvasive matrices could replace venipuncture for monitoring inflammatory status in remote or at-home settings.
Multimodal Noninvasive Assessment of C-Reactive Protein for Systemic Inflammation in Adults: Cross-Sectional Study — Shim et al., JMIR formative research
- saliva
- urine
- stool
- sweat
- venous-agreement
- acceptability
- biomarkers
2025
Non-invasive HPV self-sampling kits such as first-void urine and menstrual blood devices may increase screening participation among non-Western ethnic minority women by addressing cultural beliefs about virginity and body autonomy.
"Well, that Was Pretty Clever!"-Ethnic Minority Women's Views on HPV Self-Sampling Devices for Cervical Cancer Screening: Attitudes to Brushes, First-Void Urine, and Menstrual Blood Devices — Hald et al., Journal of racial and ethnic health disparities
- urine
- first-void
- self-collection
- acceptability
- hpv
- sti
2025
Among 154 volunteers, 85% found HemaSpot HF self-sampling acceptable, but correlation with venous blood for anti-tetanus toxin IgG was moderate (r = 0.73) and sensitivity varied from 70% to 100% depending on the cut-off value, with concentration differences widening at higher IgG levels. The device requires further improvement before it can reliably replace venous puncture for decentralised serological testing.
Feasibility of blood self-sampling with HemaSpot HF for Anti-Clostridium tetani Toxin IgG detection — Kettlitz et al., Scientific reports
- blood
- dried
- dbs
- self-collection
- venous-agreement
- acceptability
- serology
2025
Comfort Draw collected adequate capillary blood from the upper arm in 85.5 per cent of attempts for total blood volume and 95.1 per cent for serum volume, with 17 of 19 serum analytes meeting CLIA acceptance criteria against matched venous samples. The procedure scored a mean pain rating of 0.39 out of 10, indicating high patient acceptability, and the device’s simpler design may lower cost for decentralised diagnostics.
Evaluation of a Simplified Upper Arm Device for Vacuum-Assisted Collection of Capillary Blood Specimens — Schaff et al., Diagnostics
- blood
- liquid
- capillary
- validation
- venous-agreement
- acceptability
2025
The study found that dried blood spot sampling showed good agreement with plasma concentrations for vancomycin and creatinine, with most differences within 20%, and patients preferred the finger prick method over venepuncture, supporting its use for decentralised therapeutic drug monitoring.
Clinical validation of an innovative dried whole-blood spot method to quantify simultaneously vancomycin and creatinine in adult patients — Hassanzai et al., The Journal of antimicrobial chemotherapy
- blood
- dried
- dbs
- self-collection
- validation
- venous-agreement
- acceptability
- tdm
- antimicrobials
2025
Among 404 Australians at risk of hepatitis C, 91% of those with prior infection selected point-of-care RNA testing, citing rapid results, while 72% of those without prior infection preferred staff-assisted antibody testing. Offering rapid, staff-assisted testing improves uptake among people who inject drugs, those experiencing homelessness and those receiving opioid agonist therapy.
Patient preferences for simplified hepatitis C testing modalities among people at risk of hepatitis C infection in Australia: the SELECT study — Stevens et al., The International journal on drug policy (paywalled)
- blood
- capillary
- dbs
- self-collection
- acceptability
- serology
2025
Among 133 users of HIV self-sampling and self-testing in the Netherlands, the commonest reason for choosing this route was saving time, followed by anonymity and avoiding a GP visit. However, 22% encountered problems, with seven in ten of those struggling to obtain enough blood from a finger prick, showing that while self-testing expands reach, blood collection remains a key usability hurdle for decentralised HIV screening.
Self-sampling and self-testing for HIV at a commercial and community-based test provider in the Netherlands: user preferences and usability — Willemstein et al., BMC health services research
- blood
- capillary
- self-collection
- acceptability
- serology
- sti
2025
Self-sampling of dried blood spots for HIV viral load monitoring proved acceptable among sexual minority men who use stimulants, with 92% returning Tasso-M20 kits and 88% returning HemaSpot HD kits. Participants' device preferences centred on convenience and pain, and they highlighted that clearer instructions, contingency planning, and addressing intersectional stigma are essential for engagement, indicating that patient choice in sampling methods could improve uptake of decentralised diagnostics.
'I was like, this is gonna hurt': Implementing self-sampling of dried blood spots to measure HIV viral load — Chavez et al., PloS one
- blood
- dried
- dbs
- self-collection
- acceptability
- serology
2025
In surveys of 141 trial-site staff and 481 individuals, participants showed greater enthusiasm for hybrid and remote decentralised trials than site staff, who worried about burden, trust and security. Participant willingness to use trial technologies decreased with rising perceived burden, underscoring that practical support is vital for adoption in decentralised diagnostics.
Comparison of Participant and Site Perceptions of Decentralized Clinical Trials in the USA — Barge & Floody, Mayo Clinic proceedings. Digital health
- acceptability
- dct
2025
Participants in the ACTIV-6 decentralised trial viewed remote procedures supported by digital health technologies as acceptable and efficient for organising study activities, communicating with study personnel and managing medications at home, though social media recruitment raised concerns about trust and study legitimacy that future trial designs should address.
Participant experiences in a decentralized clinical trial using digital health technologies: The ACTIV-6 study — Reale et al., Journal of clinical and translational science
- acceptability
- dct
2025
In a French trial of 682 under-screened women, most found HPV self-sampling instructions clear and procedures easy, with around 80% preferring home collection over clinic visits. Urine self-sampling was better tolerated than vaginal self-sampling, suggesting it may improve participation in decentralised cervical cancer screening programmes.
Women's perceptions and preferences toward HPV self-sampling in France: A questionnaire within the French CapU4 Trial — De Pauw et al., Journal of infection and public health (paywalled)
- urine
- self-collection
- acceptability
- hpv
- sti
2025
In a decentralised phase 1 trial, healthy adults used a clinical trial app to self-collect blood microsamples and vital signs at home, with 65 to 70 per cent successfully providing blood samples and most preferring self-collection over staff collection.
Conducting clinical trials with self-collection of pharmacokinetic samples: Experience from an exploratory, phase 1, open-label trial of centanafadine SR in healthy individuals — Ye et al., Contemporary clinical trials communications
- blood
- self-collection
- acceptability
- dct
- rpm
- multimodal
2025
The study found that while decentralised clinical trials improve accessibility, they introduce complexities that can negatively affect patient engagement and the relationship between staff and participants due to limited interaction frequency and quality.
Adaptation of Clinical Research Staff to Decentralized Clinical Trials and Impacts on the Patient-Centered Experience: Qualitative Interview Study — Gamble et al., Journal of medical Internet research
- acceptability
- dct
2025
Dried blood spot sampling matched venous serum performance for islet autoantibody detection and was considered minimally invasive and convenient by parents and stakeholders, supporting its use for decentralised screening in home or community settings.
Establishing the performance and acceptability of dried blood spot sampling to screen for islet-specific autoantibodies — Faustini et al., Diabetic medicine : a journal of the British Diabetic Association
- blood
- dried
- capillary
- dbs
- self-collection
- validation
- venous-agreement
- acceptability
- pediatric
2025
Among people who inject drugs, point-of-care HCV testing was preferred over dried blood spot collection and venepuncture because rapid results reduced anxiety. The study shows that for decentralised screening, non-judgemental care and assisted collection are critical acceptability factors, even when self-collection is available.
Acceptability of hepatitis C testing using point-of-care testing and dried blood spot collection among people at risk of hepatitis C infection — Stevens et al., The International journal on drug policy (paywalled)
- blood
- dried
- dbs
- self-collection
- acceptability
- serology
2025
Urine-based HPV testing showed broad variability in diagnostic performance, with sensitivity ranging from 44.8 to 98.6 per cent and specificity from 61 to 100 per cent against cervical specimens. High patient acceptability was reported, yet standardisation is needed before this self-collection approach can be approved for decentralised cervical cancer screening.
A Narrative Review of Urine-Based Human Papillomavirus Screening: Performance, Challenges, and Opportunities to Expand Access in the United States — Yang et al., Sexually transmitted diseases (paywalled)
- urine
- self-collection
- validation
- acceptability
- hpv
- sti
2025
Urinary HPV testing showed lower sensitivity than cervical sampling for detecting CIN2+ (79% versus 93%) but higher specificity (58% versus 50%), and participants favoured urine self-collection. The authors conclude that while urine sampling may complement screening in resource-limited or culturally conservative settings, its suboptimal performance and absence of standardised protocols preclude its use for general population screening.
Pooled performance of urinary human papillomavirus (HPV) testing for the presence of cervical HPV — Ye et al., Cancer (paywalled)
- urine
- self-collection
- validation
- acceptability
- hpv
- sti
2025
Self-collected urine and vaginal samples for hrHPV and CIN2+ detection showed high diagnostic accuracy and acceptability compared with clinician sampling, supporting their use as viable alternatives that could improve screening accessibility and compliance in decentralised settings.
Feasibility and acceptability of human papillomavirus self-sampling compared with clinician sampling in urban areas of western China: a cross-sectional survey — Xue et al., Frontiers in public health
- urine
- self-collection
- acceptability
- hpv
- sti
2025
Only 24% of participants completed this two-cycle feasibility study of AI-interpreted salivary ferning for ovulation prediction in females with irregular cycles, with 44% withdrawing citing cycle irregularity, pregnancy, or time constraints. The authors concluded that decentralised fertility trials must streamline procedures and provide ovulatory health education to improve retention and reduce burden before smartphone-based diagnostics can be scaled for this population.
Digitally Enabled AI-Interpreted Salivary Ferning-Based Ovulation Prediction: Feasibility Study — Peebles et al., Journal of medical Internet research
- saliva
- self-collection
- acceptability
- fertility
- hormones
2025
Urine-based HPV testing demonstrated 74% sensitivity and 52% specificity for detecting CIN2+, with performance improving when first-void collection and PCR-based assays were used. Although less sensitive than clinician-collected cervical samples, urine testing was preferred by over 90% of women, indicating potential as a complementary screening strategy to improve uptake.
- urine
- first-void
- self-collection
- validation
- acceptability
- hpv
- sti
2025
Capillary volumetric absorptive microsampling showed significant differences in absolute antibiotic concentrations compared to venous plasma, yet it reliably tracked the pharmacokinetic profiles of amoxicillin, metronidazole, and azithromycin over time. The approach was well accepted by both participants and clinicians, indicating its feasibility for less invasive therapeutic drug monitoring in periodontal clinical trials.
A comparison between venous blood sampling and capillary volumetric absorptive microsampling for antibiotics levels monitoring in individuals with and without periodontal disease — Lazaridi et al., Clinical oral investigations
- blood
- dried
- capillary
- vams
- neoteryx-mitra
- venous-agreement
- acceptability
- tdm
- antimicrobials
2025
All five at-home urine ovulation predictor kits demonstrated high accuracy (92–97%) when compared with blood LH levels, though sensitivity varied widely from 38% to 77% with Clinical Guard the lowest. Patient experience was comparable across kits, though Clinical Guard was slightly less favoured for future use.
Similar accuracy and patient experience with different one-step ovulation predictor kits — Vanderhoff et al., Fertility and sterility (paywalled)
- blood
- urine
- self-collection
- validation
- venous-agreement
- acceptability
- fertility
- hormones
2025
Whole-genome sequencing of dried blood spots from 1,000 newborns identified 16 infants with high-chance results, most missed by standard screening. The 13-day turnaround and high parental acceptability show a feasible, scalable model for decentralised genomic screening.
Feasibility, acceptability and clinical outcomes of the BabyScreen+ genomic newborn screening study — Lunke et al., Nature medicine
- blood
- dried
- dbs
- acceptability
- pediatric
- genotyping
2025
The authors observe that self-sampling devices for capillary blood are gaining traction as a patient-preferred alternative to venous collection, with one centre reporting a 15 percent reduction in laboratory test volumes when local collection was offered. They argue that successful integration into total laboratory automation requires addressing cost, transport regulations and sample volume adequacy while ensuring robust device design and seamless workflow compatibility.
Blood self-sampling devices: innovation, interpretation and implementation in total lab automation — Poland & Cobbaert, Clinical chemistry and laboratory medicine (paywalled)
- blood
- liquid
- capillary
- self-collection
- acceptability
2024
Head-to-head clinical validation of two VAMS devices for tacrolimus and mycophenolic acid, with roughly 86–88% of samples within ±20% of venous.
Clinical validation of two volumetric absorptive microsampling devices to support home-based therapeutic drug monitoring of immunosuppression — Leino et al., British Journal of Clinical Pharmacology (paywalled)
- vams
- venous-agreement
- acceptability
- neoteryx-mitra
- blood
- tdm
- self-collection
- dried
- immunosuppressants
- validation
2024
In 91 children and adults, capillary C-peptide taken with the TAP device matched venous sampling with 100% sensitivity and specificity for a clinically relevant level, 200 pmol/L or above, with r = 0.996. 63% preferred it to a needle against 7% who preferred the needle, and same-day bruising was 5.5% versus 34.8% after a venous draw.
Transdermal blood sampling for C-peptide is a minimally invasive, reliable alternative to venous sampling in children and adults with type 1 diabetes — Besser et al., Diabetes Care
- blood
- liquid
- yourbio
- capillary
- pediatric
- venous-agreement
- acceptability
- validation
2024
In at-home and trial settings, a wet capillary device reliably collected a median ~450 µL with a 4.4% failure rate; 88% of adults preferred self-collection over venipuncture, with lower pain.
Feasibility, acceptability and safety of a device for self-collecting capillary blood in clinical trials — Dasari et al., PLOS ONE
- acceptability
- blood
- self-collection
- capillary
- pediatric
- liquid
- validation
2024
Self-collected rectal and pharyngeal specimens showed high agreement and diagnostic accuracy compared to clinician-taken samples for detecting Chlamydia trachomatis and Neisseria gonorrhoeae. The approach was highly acceptable to participants, the majority of whom preferred self-sampling to clinician-sampling.
Performance and acceptability of self-collected specimens for diagnosis of rectal and pharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae infections among men who have sex with men in China: a randomized controlled trial — Jiang et al., BMC infectious diseases
- acceptability
- first-void
- sti
- self-collection
- urine
2024
The study found excellent agreement between hCG levels measured in remotely collected capillary blood and standard venous samples, with a near-perfect correlation. This demonstrates that remote self-collection is a feasible and acceptable alternative for serial pregnancy monitoring, reducing the need for clinic visits.
Proof-of-concept study: Remote capillary blood collection for hCG analysis in early pregnancy — Joyce et al., European journal of obstetrics, gynecology, and reproductive biology (paywalled)
- venous-agreement
- acceptability
- blood
- self-collection
- capillary
- fertility
- hormones
- liquid
2024
In a cross-sectional study of 90 adolescents, 94 per cent provided at least one salivary sample and 89 per cent supplied a stool sample, with high adherence to study instructions, indicating that self-collection of these biospecimens is feasible and acceptable in this age group.
Engaging adolescents in research: Home self-collection of biological samples and health questionnaires — Leung et al., Research in nursing & health (paywalled)
- acceptability
- self-collection
- microbiome
- pediatric
- stool
- saliva
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