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OpenSampling

The Library

1530 papers on microsampling and monitoring, each with a finding paraphrased to our standard and labelled in one vocabulary. Every entry links to a legitimate copy; nothing is copied from an abstract.

3 papers labelled “sweat”, newest first.

  1. 2026

    This review establishes that microsampling across blood, saliva, urine and stool matrices offers validated workflows and regulatory recognition for human biomonitoring comparable to conventional methods. It finds that these decentralised approaches enhance participant acceptability and enable screening in remote or low-resource settings.

    Integrating Microsampling in Human Biomonitoring: Methodologies, Regulatory Frameworks, and Case Study InsightsRajamani & Poongavanam, Critical reviews in analytical chemistry (paywalled)

    • wearable
    • acceptability
    • multimodal
    • sweat
    • blood
    • dbs
    • standards
    • dried
    • serology
    • colorectal
    • pediatric
    • stool
    • urine
    • validation
    • saliva
    • biomarkers
  2. 2025

    The study validated a method for measuring cystic fibrosis drugs in dried blood spots, showing statistical equivalence to plasma concentrations, which supports their use as a less invasive alternative for therapeutic drug monitoring. It also found higher drug levels in nasal swabs, indicating localised accumulation at the disease site, which could inform more personalised treatment.

    Development and application of a multimatrix LC-MS/MS method for quantifying elexacaftor-tezacaftor-ivacaftor: Expanding therapeutic drug monitoring in cystic fibrosis from systemic circulation to airways and sweatMucci et al., Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (paywalled)

    • venous-agreement
    • sweat
    • blood
    • dbs
    • qdbs
    • tdm
    • dried
    • pediatric
    • validation
  3. 2025

    In 20 adults, CRP measured in urine and saliva strongly correlated with serum CRP (Spearman rho 0.886) and was significantly elevated in participants with systemic inflammation compared with controls, suggesting these noninvasive matrices could replace venipuncture for monitoring inflammatory status in remote or at-home settings.

    Multimodal Noninvasive Assessment of C-Reactive Protein for Systemic Inflammation in Adults: Cross-Sectional StudyShim et al., JMIR formative research

    • saliva
    • urine
    • stool
    • sweat
    • venous-agreement
    • acceptability
    • biomarkers

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