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OpenSampling

The Library

Papers on microsampling and monitoring, each with a finding paraphrased to our standard and labelled in one vocabulary. With a free account, every entry links to a legitimate copy; nothing is copied from an abstract.

Papers 1–5 of 28 labelled “Biologics”, newest first.

  1. 2026

    Microsampling of proteins from biological matrices: sampling methods and devices, typical workflows, clinical examples, novel applications and innovations

    This review finds that dried microsampling has matured from simple blood spots into diverse devices capable of therapeutic drug monitoring, multiplex biomarker profiling, and multi-omics, with integrated smart sampling and dried immunoassays now ready for field use.

    Halvorsen et al., Analytical methods (paywalled)

  2. 2026

    Recent developments in microsampling for oligonucleotides and biologics bioanalysis

    The review discusses the advantages of microsampling for bioanalysis of oligonucleotides and biologics,

    Guimaraes & Yuan, Bioanalysis (paywalled)

  3. 2025

    Development, Validation and Application of the Dried Blood Spot Analysis Method for the Determination of Ustekinumab in Patients with Inflammatory Bowel Disease

    The study found a dried blood spot method for ustekinumab was linear from 3 to 12 mg/L with inter-day

    Mingas et al., Pharmaceuticals

  4. 2025

    HematoCARD: A Volumetric Duplicate Dried Blood Spot Collection Cartridge Validated for Therapeutic Drug Monitoring

    The HematoCARD cartridge autonomously collects duplicate 10 microlitre dried blood spot samples from a single finger prick and shows good analytical performance for

    Van Hileghem et al., Analytical chemistry (paywalled)

  5. 2025

    Home-sampling of B cells using quantitative dried blood spots to enable tailored therapeutic re-dosing of anti-CD20 therapies

    This study validated a method combining quantitative dried blood spots with DNA methylation analysis to monitor B-cell counts remotely, achieving 100% sensitivity and specificity for a specific clinical threshold.

    Tallantyre et al., Multiple sclerosis (paywalled)

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