2016 · BMC Medical Genomics · open access
Gudiseva et al.
With Oragene DISCOVER self-collection, saliva SNP-array genotypes matched blood at 99.996% concordance; about 6% of samples failed on low yield, so an occasional repeat should be expected.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
2016
ORAcollect saliva matched blood at 97.9% overall variant concordance on a hereditary-cancer NGS panel, rising to 100% for protein-coding variants, supporting self-collected saliva for germline testing.
Validation of saliva as an alternative specimen for detecting hereditary breast-cancer mutations by next-generation sequencing — Meghnani et al., International J. Genomics · source ↗
2012
Oragene-stabilised saliva DNA agreed with blood at 98.7% of called markers on a pharmacogenetic array; saliva's lower overall call rate tracked its variable human-DNA content.
Genotyping Performance between Saliva and Blood-Derived Genomic DNAs on the DMET Array: A Comparison — Hu et al., PLoS ONE · source ↗
2018
Telomere length measurements vary significantly depending on the sample type used, with Oragene saliva showing a moderate correlation to venous buffy coat, whereas Oasis saliva and dried blood spots did not yield comparable or adequate results for this assay.
Evaluating minimally invasive sample collection methods for telomere length measurement — Goldman et al., American journal of human biology : the official journal of the Human Biology Council (paywalled) · source ↗
2025
This study found that a decontamination pipeline using metagenome-assembled genomes improves the accuracy of variant calling from saliva samples, showing superior concordance with blood-derived results compared to conventional methods. These results validate the potential of self-collected oral samples for accurate personal genotyping.
Metagenome-assembled genomes enhance bacterial read decontamination and variant calling in oral samples — An et al., iScience · source ↗
2026
The homeRNA capillary blood collection and stabilization platform successfully captured lipopolysaccharide-induced inflammatory gene expression profiles. These transcriptomic responses were comparable to those obtained from traditional venous blood samples stabilized with RNAlater or PAXgene, demonstrating the platform's suitability for remote transcriptomic monitoring.
From Home to Transcriptome: Comparing the Transcriptomic Profile of Induced Immune Response via Lipopolysaccharide Stimulation in homeRNA and Venous Blood — Brown et al., Analytical chemistry (paywalled) · source ↗