2024 · Clinica chimica acta; international journal of clinical chemistry · paywalled
Evaluation of measured and calculated small dense low-density lipoprotein in capillary blood and association with the metabolic syndrome
Deza et al.
The finding, in our words
Capillary blood measurement of small dense LDL cholesterol agrees with venous sampling and remains stable for 24 hours at room temperature. This validates patient-centric microsampling for decentralised cardiovascular risk assessment in metabolic syndrome.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
The homeRNA capillary blood collection and stabilization platform successfully captured lipopolysaccharide-induced inflammatory gene expression profiles. These transcriptomic responses were comparable to those obtained from traditional venous blood samples stabilized with RNAlater or PAXgene, demonstrating the platform's suitability for remote transcriptomic monitoring.
Brown et al., Analytical chemistry (paywalled) · source ↗
The True Dose TD-EPI kit demonstrated strong analytical agreement with venous blood for epirubicin monitoring, and the capillary samples remained stable for 72 hours at ambient temperature.
Self-collected capillary blood samples posted by standard mail showed high concordance with couriered venous samples for HbA1c, creatinine and lipid parameters, supporting their use for remote monitoring in diabetes management and screening.
Hoffmeister et al., Journal of diabetes investigation · source ↗
Plasma lipidomes from self-collected upper-arm capillary blood were statistically indistinguishable from paired venous plasma, most classes at r=0.95–0.99, validating at-home capillary self-collection for lipidomics.
A 2025 review maps 28 microsampling devices, from dried spots and volumetric absorptive tips to upper-arm liquid capillary collectors, and names what a laboratory must control before their results are used: the haematocrit effect in non-volumetric dried samples, interstitial fluid from finger milking, volume, haemolysis and transport stability. Regulators on both sides of the Atlantic ask for the same two things, a device the patient can use safely and a sample fit for the test.