2019 · British Journal of Clinical Pharmacology · open access
Berends et al.
A clinical validation showing dried blood samples can support infliximab concentration monitoring in inflammatory bowel disease.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
2017
Finger-prick dried blood spots supported monitoring of both adalimumab and anti-adalimumab antibodies in inflammatory rheumatic disease: biologic TDM without a venous draw.
Dried blood spots from finger prick facilitate therapeutic drug monitoring of adalimumab and anti-adalimumab in patients with inflammatory rheumatic diseases — Kneepkens et al., British Journal of Clinical Pharmacology (paywalled) · source ↗
2026
In AML and CLL, 91% of VAMS venetoclax results fell within 20% of plasma after individualised haematocrit correction; in home sampling, 18 of 21 patients self-sampled independently and 76% of returned samples were analysable, which shows home microsampling is workable, though the authors ask for multicentre validation.
Clinical Validation of Venetoclax Volumetric Microsampling in Leukemia, with Whole-Blood-to-Plasma Conversion and Self-Microsampling Feasibility — Levens et al., Clinical Pharmacokinetics (paywalled) · source ↗
2026
Home DBS sampling gave testosterone results that agreed well with venous blood in men on intramuscular testosterone undecanoate, but showed falsely high values in those using topical gel, likely from skin contamination. Patients preferred home collection for its convenience, suggesting DBS is viable for decentralised monitoring of injectable testosterone if patients are taught proper technique.
From venipuncture to self-sampling dried blood spots: a shift in monitoring testosterone levels — Olthof et al., Clinical chemistry and laboratory medicine (paywalled) · source ↗
2025
Capillary dried blood spot concentrations of levetiracetam agreed closely with plasma, with 92.1% within 20% of the mean and no proportional bias, and capillary matched venous dried blood spot with acceptable deviations; samples remained stable during postal transit, enabling at‑home self‑sampling for therapeutic drug monitoring.
Therapeutic drug monitoring of levetiracetam - Is dried blood spot sampling suitable? — Linder et al., Clinical biochemistry (paywalled) · source ↗
2025
The study found that dried blood spot sampling showed good agreement with plasma concentrations for vancomycin and creatinine, with most differences within 20%, and patients preferred the finger prick method over venepuncture, supporting its use for decentralised therapeutic drug monitoring.
Clinical validation of an innovative dried whole-blood spot method to quantify simultaneously vancomycin and creatinine in adult patients — Hassanzai et al., The Journal of antimicrobial chemotherapy · source ↗