Timed saliva sampling as a new reliable marker for assessing iodine intake
Oblak et al.
The finding, in our words
In 104 healthy adults who collected both 24-hour urine and saliva at home, salivary iodine concentration measured at specific post-meal intervals showed excellent correlation with urinary iodine excretion. This suggests timed saliva microsampling could replace cumbersome urine collection as a reliable biomarker for assessing iodine intake in decentralised diagnostics.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
This review found saliva comparable to blood and urine for detecting viral genetic material and antibodies, supporting patient-centric monitoring and decentralised surveillance. The authors state that standardised protocols and further validation are required for routine clinical use.
This review establishes that microsampling across blood, saliva, urine and stool matrices offers validated workflows and regulatory recognition for human biomonitoring comparable to conventional methods. It finds that these decentralised approaches enhance participant acceptability and enable screening in remote or low-resource settings.
This review summarises how incorporating saliva and urine into home-based point-of-care systems expands diagnostic accessibility for dengue virus, aligning with the WHO REASSURED framework for affordable and rapid testing.
Shi et al., Journal of medical virology (paywalled) · source ↗
This paper describes a handheld electrochemical sensor for vitamin C measurement in saliva and urine, showing a linear range from 0.2 to 200 µm and detection limit of 0.03 µm. The device demonstrated satisfactory accuracy and recovery in human samples, suggesting potential for affordable home-based testing of vitamin C status.
Fu et al., Advanced healthcare materials (paywalled) · source ↗
Self-collected urine samples detected high-risk HPV DNA in 25.5 per cent of women and 8 per cent of men by qPCR, while oral gargle samples detected HPV in 7 per cent of women and 5 per cent of men. With good diagnostic accuracy against Pap smear, qPCR on self-collected specimens offers a viable decentralised approach to HPV screening in remote populations.
Gupta et al., The Indian journal of medical research · source ↗