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OpenSampling

2018 · Metabolomics · paywalled

Quantitative metabolomics comparison of traditional blood draws and TAP capillary blood collection

Catala et al.

The finding, in our words

Metabolomics of TAP capillary blood matched venous draws for most metabolites, amino acids, bile acids and acyl-carnitines at r≥0.95; a small redox/energy subset differed with collection dynamics.

A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.

Labels

  1. 2025

    A head-to-head of four upper-arm capillary devices, including TAP Micro Select, versus fingerstick and venous: experience and performance varied by device with none clearly superior, while analyte correlations with venous were similar across all.

    Comparing capillary blood collection technologies: patient experience, device performance and clinical accuracyCollier et al., Bioanalysis (paywalled) · source ↗

    • blood
    • liquid
    • yourbio
    • capillary
    • venous-agreement
    • acceptability
    • validation
    • bd-microtainer
  2. 2025

    Plasma lipidomes from self-collected upper-arm capillary blood were statistically indistinguishable from paired venous plasma, most classes at r=0.95–0.99, validating at-home capillary self-collection for lipidomics.

    Comparison of capillary and venous plasma lipidomes: validation of self-collected blood for plasma lipidomicsHameed et al., J. Lipid Research · source ↗

    • venous-agreement
    • blood
    • metabolome
    • self-collection
    • capillary
    • liquid
    • validation
    • biomarkers
  3. 2025

    In 46 women under hormone monitoring at Columbia University Fertility Center, oestradiol, LH, FSH, progesterone and hCG measured on routine immunoassays from 400 to 600 microlitres of upper-arm capillary blood collected with TAP Micro Select agreed closely with paired venous results for every analyte, with correlation and concordance high throughout. It is the evidence that puts a self-collected sample inside the daily monitoring of an IVF cycle.

    Painless, needle-free capillary blood collection for fertility hormone monitoringLattin et al., Fertility and sterility (paywalled) · source ↗

    • blood
    • liquid
    • capillary
    • yourbio
    • fertility
    • hormones
    • venous-agreement
    • validation
  4. 2024

    In 91 children and adults, capillary C-peptide taken with the TAP device matched venous sampling with 100% sensitivity and specificity for a clinically relevant level, 200 pmol/L or above, with r = 0.996. 63% preferred it to a needle against 7% who preferred the needle, and same-day bruising was 5.5% versus 34.8% after a venous draw.

    Transdermal blood sampling for C-peptide is a minimally invasive, reliable alternative to venous sampling in children and adults with type 1 diabetesBesser et al., Diabetes Care · source ↗

    • blood
    • liquid
    • yourbio
    • capillary
    • pediatric
    • venous-agreement
    • acceptability
    • validation
  5. 2023

    TAP II capillary serum, both professionally collected and self-collected, correlated with venous serum at R > 0.9 for eight analytes including ALT, AST, cholesterol, HDL and triglycerides. Creatinine correlated acceptably but carried a consistent negative bias, and carbon dioxide, potassium and albumin did not reach acceptable agreement: the useful reading is that the panel has to be validated, not the device alone.

    Maximizing microsampling: measurement of comprehensive metabolic and lipid panels using a novel capillary blood collection deviceCollier et al., The Journal of Applied Laboratory Medicine (paywalled) · source ↗

    • venous-agreement
    • blood
    • self-collection
    • capillary
    • bd-microtainer
    • liquid
    • yourbio
    • validation
    • biomarkers