2023 · Journal of mass spectrometry and advances in the clinical lab · open access
Matrix-matched calibrators are necessary for robust and high-quality dried blood spots lead screening assays by inductively coupled plasma-mass spectrometry
Franco et al.
The finding, in our words
Lead can be measured accurately in dried blood spots by ICP-MS only when matrix-matched calibrators are used; aqueous calibrators perform poorly. The three methods evaluated showed strong agreement with whole blood analysis and offer a robust option for decentralised lead screening in children, though the recognised limitations of dried blood spots remain.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
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