Late Eating Is Associated with Obesity, Inflammatory Markers and Circadian-Related Disturbances in School-Aged Children
Martínez-Lozano et al.
The finding, in our words
School-aged children who consumed dinner late exhibited higher rates of obesity, elevated inflammatory markers, and circadian alterations including delayed body temperature phases and reduced cortisol amplitude.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
The study demonstrated that longitudinal remote monitoring using wearable sleep electroencephalography, actigraphy, and self-collected saliva samples is feasible in older adults with mild cognitive impairment or dementia, with high retention and data completeness rates over eight weeks.
The study found that a heat-treated probiotic formulation did not significantly improve sleep scores in the full cohort but did modulate endocrine markers, showing up-regulated nocturnal melatonin and improved daytime orexin levels, with a tendency toward reduced nocturnal salivary cortisol. Benefits were more pronounced in participants with higher baseline insomnia severity, suggesting the intervention may be most useful for symptomatic populations.
In a 14-day study of youth with neurodevelopmental conditions and chronic pain, multimodal in-home monitoring achieved good accelerometer wear compliance (77% wore devices for at least 7 days) and moderate survey engagement, but adherence to salivary cortisol sampling was low at 28% after excluding protocol violations and dry swabs. Families reported high overall satisfaction and willingness to participate again, highlighting that remote sampling protocols in pediatric populations require iterative tailoring to improve biospecimen collection adherence.
Boerner et al., Journal of developmental and behavioral pediatrics : JDBP · source ↗
In youth aged 8–16 years, first-waking saliva cortisol, IL-6 and IL-1β collected at home associate with prior-night actigraphy sleep metrics. Sleep quality confounds interpretation of salivary stress and immune biomarkers in decentralised paediatric microsampling, so protocols must account for it.
LaVoy et al., International journal of psychophysiology : official journal of the International Organization of Psychophysiology (paywalled) · source ↗
This review establishes that microsampling across blood, saliva, urine and stool matrices offers validated workflows and regulatory recognition for human biomonitoring comparable to conventional methods. It finds that these decentralised approaches enhance participant acceptability and enable screening in remote or low-resource settings.