High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow immunoassay (LFIA)

Earlobe capillary microsampling of 100-250 µL found good agreement with venous draws for progesterone, concordance 0.911, and 17β-estradiol, concordance 0.919, across menstrual cycles, showing suitability for decentralised monitoring. However, participant-reported burden was not assessed, and further validation is required in elite athletes.

Larger-volume capillary blood sampling is a valid alternative to assess progesterone and 17β-estradiol for cycle phase identification — Schlie et al., Frontiers in Physiology · source ↗

• blood
• liquid
• capillary
• hormones
• fertility
• venous-agreement
• validation

In 46 women under hormone monitoring at Columbia University Fertility Center, oestradiol, LH, FSH, progesterone and hCG measured on routine immunoassays from 400 to 600 microlitres of upper-arm capillary blood collected with TAP Micro Select agreed closely with paired venous results for every analyte, with correlation and concordance high throughout. It is the evidence that puts a self-collected sample inside the daily monitoring of an IVF cycle.

Painless, needle-free capillary blood collection for fertility hormone monitoring — Lattin et al., Fertility and sterility (paywalled) · source ↗

• blood
• liquid
• capillary
• yourbio
• fertility
• hormones
• venous-agreement
• validation

The homeRNA capillary blood collection and stabilization platform successfully captured lipopolysaccharide-induced inflammatory gene expression profiles. These transcriptomic responses were comparable to those obtained from traditional venous blood samples stabilized with RNAlater or PAXgene, demonstrating the platform's suitability for remote transcriptomic monitoring.

From Home to Transcriptome: Comparing the Transcriptomic Profile of Induced Immune Response via Lipopolysaccharide Stimulation in homeRNA and Venous Blood — Brown et al., Analytical chemistry (paywalled) · source ↗

• venous-agreement
• stabilised
• blood
• capillary
• liquid
• validation
• biomarkers

In pregnant women at high risk of gestational diabetes, the GTT@home capillary glucose device showed a small positive bias of 0.16 mmol/L versus venous laboratory OGTT, with 79.8 per cent of results in the lowest surveillance risk zone and diagnostic classification agreement in 54 of 61 cases, suggesting it could support home OGTT in pregnancy.

Use of the GTT@home Oral Glucose Tolerance Test Kit in Gestational Diabetes Mellitus: Performance Evaluation Study — Dunseath et al., JMIR diabetes · source ↗

• blood
• liquid
• capillary
• validation
• venous-agreement

The True Dose TD-EPI kit demonstrated strong analytical agreement with venous blood for epirubicin monitoring, and the capillary samples remained stable for 72 hours at ambient temperature.

Method-Comparison Validation of a Novel Capillary Blood Collection Kit, True Dose<sup>®</sup> TD-EPI, for Therapeutic Drug Monitoring of Epirubicin — De Chiara et al., Pharmaceuticals · source ↗

• venous-agreement
• stabilised
• blood
• tdm
• oncology
• capillary
• liquid
• validation