Associations Among Cardiometabolic Risk Factors, Sleep Duration, and Obstructive Sleep Apnea in a Southeastern US Rural Community: Cross-Sectional Analysis From the SLUMBRx-PONS Study
Knowlden et al.
The finding, in our words
In a rural community sample of 47 adults, shorter sleep duration measured by wrist actigraphy correlated with higher BMI and blood pressure, while sleep apnea severity associated with triglycerides and glucose. The combination of sleep and cardiometabolic measures explained 25-38% of variance in sleep outcomes, suggesting remote monitoring can reveal relationships between sleep and cardiometabolic risk.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
The High-Definition Oncology feasibility study in 30 women with metastatic cancer demonstrated high adherence to biospecimen collection (97.4% plasma, 80.7% stool) and wearable monitoring (70–95% of days captured for activity, heart rate, sleep, and oxygen saturation). This establishes a viable framework for decentralised, multimodal data collection in oncology to support individualised treatment models.
Garma et al., JCO precision oncology (paywalled) · source ↗
Merck describes a digitally enabled, patient-centric trial initiative that combines outpatient PK/PD sampling with digital biomarkers and smart dosing technologies to improve exposure-response understanding and reduce patient burden, while acknowledging adoption challenges.
Dockendorf et al., Clinical and translational science · source ↗
In progressive multiple sclerosis, higher serum neurofilament light chain levels were associated with reduced daily step counts from wearables, while higher step counts were linked to lower sNfL. A ten percent increase in steps corresponded to a 0.015 decrease in sNfL z-score, suggesting rising sNfL may predict subsequent mobility decline.
Joseph et al., Annals of clinical and translational neurology (paywalled) · source ↗
Among 126 Australian university staff, age was the primary correlate of telomere length. Burnout, sleep-related impairment, and mental quality of life moderated the association between fasting plasma glucose and telomere length, showing that combining wearable-measured sleep and autonomic data with blood biomarkers can reveal how mental and cardiometabolic health interact in occupational populations.
Khanal et al., Experimental gerontology (paywalled) · source ↗
Among military conscripts, hydrolysed milk protein alone attenuated the rise in C‑reactive protein over eight weeks relative to protein plus heat‑killed probiotic, while smartwatch‑derived activity and recovery metrics showed no between‑group differences. This indicates that consumer‑grade wearables may be insensitive to immune‑modulation effects that are detectable in serum biomarkers.
Otto et al., Clinical nutrition ESPEN (paywalled) · source ↗