Effect of hydrolyzed milk proteins and postbiotic Lacticaseibacillus rhamnosus GG on inflammatory responses in conscripts: A randomized double-blind pilot trial
Otto et al.
The finding, in our words
Among military conscripts, hydrolysed milk protein alone attenuated the rise in C‑reactive protein over eight weeks relative to protein plus heat‑killed probiotic, while smartwatch‑derived activity and recovery metrics showed no between‑group differences. This indicates that consumer‑grade wearables may be insensitive to immune‑modulation effects that are detectable in serum biomarkers.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
In progressive multiple sclerosis, higher serum neurofilament light chain levels were associated with reduced daily step counts from wearables, while higher step counts were linked to lower sNfL. A ten percent increase in steps corresponded to a 0.015 decrease in sNfL z-score, suggesting rising sNfL may predict subsequent mobility decline.
Joseph et al., Annals of clinical and translational neurology (paywalled) · source ↗
Among 126 Australian university staff, age was the primary correlate of telomere length. Burnout, sleep-related impairment, and mental quality of life moderated the association between fasting plasma glucose and telomere length, showing that combining wearable-measured sleep and autonomic data with blood biomarkers can reveal how mental and cardiometabolic health interact in occupational populations.
Khanal et al., Experimental gerontology (paywalled) · source ↗
The Human Phenotype Project enrolled 28,000 participants in a deep-phenotyping cohort that combines blood and microbiome sampling with continuous glucose and sleep monitoring. An AI model trained on dietary and glucose data predicted disease onset more accurately than existing methods, showing how integrating continuous digital signals with multi-omic data can support personalised risk assessment for decentralised diagnostics.
Reicher et al., Nature medicine (paywalled) · source ↗
The study demonstrated that longitudinal remote monitoring using wearable sleep electroencephalography, actigraphy, and self-collected saliva samples is feasible in older adults with mild cognitive impairment or dementia, with high retention and data completeness rates over eight weeks.
The study demonstrates that frequent collection of 10 microlitres of capillary blood, combined with wearable sensor data, enables simultaneous measurement of thousands of metabolites, lipids, cytokines and proteins, revealing individualised metabolic and inflammatory responses to dietary interventions and molecular fluctuations linked to intra-day changes in heart rate, glucose, cortisol and physical activity, supporting dynamic health profiling outside the clinic.
Shen et al., Nature biomedical engineering · source ↗