2014 · Clinical chemistry and laboratory medicine · paywalled
System accuracy evaluation of systems for point-of-care testing of blood glucose: a comparison of a patient-use system with six professional-use systems
Freckmann et al.
The finding, in our words
A patient-use blood glucose monitoring system achieved accuracy comparable to six professional-use point-of-care systems when capillary samples from 100 subjects were measured by trained staff under standardised conditions, with all seven systems showing 99.5 to 100 per cent of results within ISO 15197:2003 limits. This supports the case that decentralised, patient-centric capillary blood glucose measurement can match professional laboratory-aligned performance when sampling is standardised.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
The homeRNA capillary blood collection and stabilization platform successfully captured lipopolysaccharide-induced inflammatory gene expression profiles. These transcriptomic responses were comparable to those obtained from traditional venous blood samples stabilized with RNAlater or PAXgene, demonstrating the platform's suitability for remote transcriptomic monitoring.
Brown et al., Analytical chemistry (paywalled) · source ↗
In pregnant women at high risk of gestational diabetes, the GTT@home capillary glucose device showed a small positive bias of 0.16 mmol/L versus venous laboratory OGTT, with 79.8 per cent of results in the lowest surveillance risk zone and diagnostic classification agreement in 54 of 61 cases, suggesting it could support home OGTT in pregnancy.
The POC haemoglobin device showed moderate correlation with laboratory values but was not accurate enough for routine monitoring; however, it had a high negative predictive value at the 7 g/dL threshold, meaning it can reliably rule out severe anaemia and may help avoid unnecessary transfusions and hospital visits if confirmed in larger studies.
The True Dose TD-EPI kit demonstrated strong analytical agreement with venous blood for epirubicin monitoring, and the capillary samples remained stable for 72 hours at ambient temperature.
This UK consensus opinion outlines how clinical laboratories can validate self-collected capillary blood sampling against venous reference standards to achieve accreditation and facilitate the shift towards community-based patient care.
Woolley et al., Annals of clinical biochemistry (paywalled) · source ↗