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OpenSampling

2024 · Endocrine · open access

Short fasting test as a reliable and effective tool to diagnose insulinoma

Mikovic et al.

The finding, in our words

A short fasting test initiated overnight at home and completed in an outpatient setting diagnosed insulinoma in 11 of 12 patients within 24 hours (91.7% sensitivity). This decentralised approach avoids prolonged inpatient monitoring while maintaining diagnostic accuracy.

A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.

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  1. 2024

    The study found excellent agreement between hCG levels measured in remotely collected capillary blood and standard venous samples, with a near-perfect correlation. This demonstrates that remote self-collection is a feasible and acceptable alternative for serial pregnancy monitoring, reducing the need for clinic visits.

    Proof-of-concept study: Remote capillary blood collection for hCG analysis in early pregnancyJoyce et al., European journal of obstetrics, gynecology, and reproductive biology (paywalled) · source ↗

    • venous-agreement
    • acceptability
    • blood
    • self-collection
    • capillary
    • fertility
    • hormones
    • liquid
  2. 2026

    This UK consensus opinion outlines how clinical laboratories can validate self-collected capillary blood sampling against venous reference standards to achieve accreditation and facilitate the shift towards community-based patient care.

    UK recommendations for the validation and adoption of capillary blood testing within the routine clinical laboratory: Consensus opinion from the LabMed patient-centred testing and sampling (PaCTS) groupWoolley et al., Annals of clinical biochemistry (paywalled) · source ↗

    • venous-agreement
    • blood
    • standards
    • self-collection
    • capillary
    • liquid
    • validation
  3. 2026

    Capillary blood samples collected by staff or self-collected by participants showed strong correlation and clinically acceptable agreement with venipuncture for influenza haemagglutination inhibition titers. The small differences observed were not clinically meaningful, and adequate sample volume was achieved in most attempts, supporting the feasibility of decentralised serological testing.

    Comparison of influenza hemagglutination inhibition titers from capillary blood versus venipunctureRick et al., Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology (paywalled) · source ↗

    • blood
    • liquid
    • capillary
    • self-collection
    • validation
    • venous-agreement
    • serology
  4. 2026

    This study found strong concordance between capillary samples collected via the Tasso device and standard venous draws for VirScan serology, indicating that self-collected samples are a practical alternative for decentralised research. The authors advise against interchanging these collection methods within a single longitudinal study to avoid introducing technical variability.

    Assessing VirScan serosurvey epitope profiling variability between in-clinic venous blood draw and capillary blood self-sampling deviceSircy et al., Microbiology spectrum · source ↗

    • dct
    • venous-agreement
    • blood
    • self-collection
    • serology
    • capillary
    • liquid
  5. 2026

    Self-collected capillary blood samples posted by standard mail showed high concordance with couriered venous samples for HbA1c, creatinine and lipid parameters, supporting their use for remote monitoring in diabetes management and screening.

    Concordance of HbA1c, creatinine, LDL cholesterol, HDL cholesterol, and total cholesterol between venous and self-collected capillary blood samples sent by mailHoffmeister et al., Journal of diabetes investigation · source ↗

    • venous-agreement
    • blood
    • self-collection
    • capillary
    • liquid
    • validation
    • biomarkers