Prevalence of syphilis and chlamydia trachomatis infection among men who have sex with men in Jiangsu province, China: A cross-sectional survey

The study found comparable seropositivity for Chlamydia trachomatis and Toxoplasma gondii among male partners of infertile couples in Odisha, with 28 per cent showing anti-Chlamydia IgA and 28 per cent anti-Toxoplasma IgM antibodies. This demonstrates that first-void urine and seminal fluid can detect relevant infections, supporting their use in decentralised fertility screening programmes.

Seropositivity of <i>Chlamydia trachomatis & Toxoplasma gondii</i> among male partners of infertile couples in Odisha, India: A facility-based exploratory study — Naik et al., The Indian journal of medical research · source ↗

• first-void
• blood
• sti
• serology
• fertility
• urine

In 250 Iranian infertile couples followed for 24 months, detection of Chlamydia trachomatis DNA in first-void urine, semen or serum antibodies did not predict tubal factor infertility, pregnancy rate or outcome. This indicates that patient-collected first-void urine screening for these organisms may have limited clinical utility in fertility assessment.

Relationship between Chlamydia trachomatis and Mycoplasma genitalium infection and pregnancy rate and outcome in Iranian infertile couples — Dehghan Marvast et al., Andrologia (paywalled) · source ↗

• blood
• urine
• first-void
• fertility
• serology
• sti

The study of 250 infertile men found that Chlamydia trachomatis infection detected in first-void urine by PCR was associated with lower semen volume, while seminal interleukin levels showed non-significant elevation. This supports the use of patient-centric first-void urine and blood samples for screening sexually transmitted infections in decentralised fertility diagnostics.

Semen inflammatory markers and Chlamydia trachomatis infection in male partners of infertile couples — Dehghan Marvast et al., Andrologia (paywalled) · source ↗

• first-void
• blood
• sti
• serology
• fertility
• urine

The cross-sectional survey of 1541 HIV-positive men found high rates of genital mycoplasma co-infection, Ureaplasma urealyticum in 26.7 per cent and Mycoplasma hominis in 25.3 per cent, using first-void urine. This demonstrates the clinical value of urine-based screening for STI co-infection surveillance in HIV cohorts within decentralised diagnostic workflows.

Epidemiology of Mycoplasma acquisition in male HIV-1 infected patients: a multistage cross-sectional survey in Jiangsu, China — Chen et al., Epidemiology and infection (paywalled) · source ↗

• blood
• urine
• first-void
• serology
• sti

First-void urine samples showed significantly higher detection rates of HPV-specific IgG antibodies compared to midstream urine, confirming the necessity of capturing the initial stream. The study found no significant difference between 10 mL and 20 mL collection volumes, indicating flexibility in device specifications for self-collection.

The importance of first-void urine for assessing HPV-specific antibodies: A comparison with midstream urine — Van Caesbroeck et al., Human vaccines & immunotherapeutics · source ↗

• first-void
• sti
• self-collection
• serology
• hpv
• urine