Impact of blood volume, air exposure duration, transport duration, and testing delay on plasma total carbon dioxide in simulated open collections using microtainers

Although most kidney transplant recipients successfully collected capillary blood samples at home, haemolysis and transport conditions affected analyte stability. Agreement with venous sampling was acceptable for haemoglobin and creatinine, but potassium and haematocrit exceeded total allowable error limits.

At-home blood collection for clinical chemistry analyses in a kidney transplant population: a feasibility study — Hoekstra et al., Clinical chemistry and laboratory medicine (paywalled) · source ↗

• blood
• liquid
• capillary
• bd-microtainer
• self-collection
• validation
• venous-agreement

A head-to-head of four upper-arm capillary devices, including TAP Micro Select, versus fingerstick and venous: experience and performance varied by device with none clearly superior, while analyte correlations with venous were similar across all.

Comparing capillary blood collection technologies: patient experience, device performance and clinical accuracy — Collier et al., Bioanalysis (paywalled) · source ↗

• blood
• liquid
• yourbio
• capillary
• venous-agreement
• acceptability
• validation
• bd-microtainer

A vacuum-assisted upper-arm device collected a mean 538 µL and met the volume target in 85.5% of cases; 17 of 19 analytes met CLIA agreement with venous, with pain lower than fingerstick.

Evaluation of a Simplified Upper-Arm Device for Vacuum-Assisted Collection of Capillary Blood — Schaff et al., Diagnostics · source ↗

• blood
• liquid
• capillary
• venous-agreement
• acceptability
• validation
• bd-microtainer

A study of decentralised patient-centric microsampling found that 82% of untrained participants, 47 of 57, successfully self-collected acceptable fingerstick blood in Microtainer tubes. All 46 tested samples yielded accurate HIV viral suppression results compared to venipuncture, though this remote monitoring approach is limited to US courier services and temperature conditions.

A cross-sectional analysis of fingerstick blood self-microcollection for remote HIV suppression monitoring in Atlanta, Georgia, USA: a path to expanding access to continuum of care — Johnson et al., AIDS research and therapy · source ↗

• blood
• liquid
• capillary
• bd-microtainer
• self-collection
• validation
• venous-agreement
• serology

A prospective study of 109 subjects found that 250 μl capillary whole blood microsampling is stable for five hours in a microtainer. This patient-centric, decentralised method successfully detected most HCV genotypes at defined limits using the Xpert HCV test on the GeneXpert Xpress system and the cobas HCV platform.

Independent assessment of a point of care HCV RNA test by laboratory analytical testing and a prospective field study in the U.S — Miller et al., PloS one · source ↗

• blood
• liquid
• capillary
• bd-microtainer
• validation
• serology