Feasibility of home-based sampling of salivary cortisol and cortisone in healthy adults
Sørensen et al.
The finding, in our words
Nineteen healthy adults showed high compliance to a three-day home salivary sampling protocol, with 95% collecting the correct number of samples. Morning cortisol and cortisone profiles had moderate reproducibility, requiring three to four days of sampling to achieve high reliability, indicating that home-based protocols can support decentralised stress-hormone monitoring.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
This study found that salivary 11-dehydrodexamethasone correlates strongly with serum dexamethasone, unlike salivary dexamethasone which shows poor agreement. This validation suggests patients could self-collect saliva samples at home to verify dexamethasone absorption for the overnight suppression test.
This study validated a lateral flow fluorescence assay using quantum dots for saliva and europium nanoparticles for serum to detect cortisol within physiological ranges. The test operates in 15 minutes with a handheld reader, supporting point-of-care and at-home monitoring without a cold chain.
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