2014 · American journal of clinical pathology · paywalled
Evaluation of the Sebia CAPILLARYS 2 flex piercing for the measurement of HbA(1c) on venous and capillary blood samples
Heylen et al.
The finding, in our words
Both the Sebia CAPILLARYS 2 Flex Piercing and the Tosoh G8 performed excellently for HbA1c determination with low imprecision and minimal bias. Capillary blood analysed on the Cap 2FP showed good agreement with venous blood and was stable at room temperature, making it an acceptable alternative for point of care testing and enabling home collection with central analysis to reduce healthcare costs without compromising quality.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
The homeRNA capillary blood collection and stabilization platform successfully captured lipopolysaccharide-induced inflammatory gene expression profiles. These transcriptomic responses were comparable to those obtained from traditional venous blood samples stabilized with RNAlater or PAXgene, demonstrating the platform's suitability for remote transcriptomic monitoring.
In pregnant women at high risk of gestational diabetes, the GTT@home capillary glucose device showed a small positive bias of 0.16 mmol/L versus venous laboratory OGTT, with 79.8 per cent of results in the lowest surveillance risk zone and diagnostic classification agreement in 54 of 61 cases, suggesting it could support home OGTT in pregnancy.
The True Dose TD-EPI kit demonstrated strong analytical agreement with venous blood for epirubicin monitoring, and the capillary samples remained stable for 72 hours at ambient temperature.
This UK consensus opinion outlines how clinical laboratories can validate self-collected capillary blood sampling against venous reference standards to achieve accreditation and facilitate the shift towards community-based patient care.
Capillary blood samples collected by staff or self-collected by participants showed strong correlation and clinically acceptable agreement with venipuncture for influenza haemagglutination inhibition titers. The small differences observed were not clinically meaningful, and adequate sample volume was achieved in most attempts, supporting the feasibility of decentralised serological testing.