Evaluation of a Novel Capillary Blood Collection System for Blood Sampling in Nontraditional Settings as Compared with Currently Marketed Capillary and Venous Blood Collection Systems for Selected General Chemistry Analytes

The homeRNA capillary blood collection and stabilization platform successfully captured lipopolysaccharide-induced inflammatory gene expression profiles. These transcriptomic responses were comparable to those obtained from traditional venous blood samples stabilized with RNAlater or PAXgene, demonstrating the platform's suitability for remote transcriptomic monitoring.

From Home to Transcriptome: Comparing the Transcriptomic Profile of Induced Immune Response via Lipopolysaccharide Stimulation in homeRNA and Venous Blood — Brown et al., Analytical chemistry (paywalled) · source ↗

• venous-agreement
• stabilised
• blood
• capillary
• liquid
• validation
• biomarkers

In pregnant women at high risk of gestational diabetes, the GTT@home capillary glucose device showed a small positive bias of 0.16 mmol/L versus venous laboratory OGTT, with 79.8 per cent of results in the lowest surveillance risk zone and diagnostic classification agreement in 54 of 61 cases, suggesting it could support home OGTT in pregnancy.

Use of the GTT@home Oral Glucose Tolerance Test Kit in Gestational Diabetes Mellitus: Performance Evaluation Study — Dunseath et al., JMIR diabetes · source ↗

• blood
• liquid
• capillary
• validation
• venous-agreement

The True Dose TD-EPI kit demonstrated strong analytical agreement with venous blood for epirubicin monitoring, and the capillary samples remained stable for 72 hours at ambient temperature.

Method-Comparison Validation of a Novel Capillary Blood Collection Kit, True Dose<sup>®</sup> TD-EPI, for Therapeutic Drug Monitoring of Epirubicin — De Chiara et al., Pharmaceuticals · source ↗

• venous-agreement
• stabilised
• blood
• tdm
• oncology
• capillary
• liquid
• validation

This UK consensus opinion outlines how clinical laboratories can validate self-collected capillary blood sampling against venous reference standards to achieve accreditation and facilitate the shift towards community-based patient care.

UK recommendations for the validation and adoption of capillary blood testing within the routine clinical laboratory: Consensus opinion from the LabMed patient-centred testing and sampling (PaCTS) group — Woolley et al., Annals of clinical biochemistry (paywalled) · source ↗

• venous-agreement
• blood
• standards
• self-collection
• capillary
• liquid
• validation

Capillary blood samples collected by staff or self-collected by participants showed strong correlation and clinically acceptable agreement with venipuncture for influenza haemagglutination inhibition titers. The small differences observed were not clinically meaningful, and adequate sample volume was achieved in most attempts, supporting the feasibility of decentralised serological testing.

Comparison of influenza hemagglutination inhibition titers from capillary blood versus venipuncture — Rick et al., Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology (paywalled) · source ↗

• blood
• liquid
• capillary
• self-collection
• validation
• venous-agreement
• serology