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OpenSampling

2023 · JMIR research protocols · open access

Engaging Black or African American and Hispanic or Latino Men Who Have Sex With Men for HIV Testing and Prevention Services Through Technology: Protocol for the iSTAMP Comparative Effectiveness Trial

Dana et al.

The finding, in our words

This protocol paper describes a decentralised HIV self-testing trial that enrolled 2093 Black and Hispanic men who have sex with men across 11 US states. The study incorporates laboratory analysis of participant-returned dried blood spot cards to verify self-reported HIV status, illustrating how patient-centric microsampling can be integrated into remote serology screening for underserved populations.

A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.

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  1. 2026

    A Narrative Review of Remote Biospecimen Collection Product and Implementation Considerations for Sexual Health Clinical Research

    This narrative review surveys remote biospecimen collection products for sexual health research, including dried blood spots and volumetric absorptive microsampling, and concludes that successful implementation needs a multidisciplinary, participant-centred team with sufficient time allocated to the complexities of collection procedures and processes.

    Horvath et al., AIDS and behavior (paywalled) · source ↗

    • blood
    • dried
    • vams
    • dbs
    • self-collection
    • validation
    • dct
    • serology
    • sti
  2. 2024

    Effectiveness of integrating HIV prevention within sexual reproductive health services with or without peer support among adolescents and young adults in rural KwaZulu-Natal, South Africa (Isisekelo Sempilo): 2 × 2 factorial, open-label, randomised controlled trial

    Self-collected dried blood spots were used to assess HIV status at 12 months in 1168 participants. Integration of sexual and reproductive health services increased linkage to HIV prevention care within 60 days (adjusted odds ratio 1·68) compared with standard referral, whereas peer support had no effect.

    Shahmanesh et al., The lancet. HIV (paywalled) · source ↗

    • blood
    • dried
    • dbs
    • self-collection
    • dct
    • serology
    • sti
  3. 2026

    Prevalence of chlamydial, gonococcal and syphilis positivity by anatomical site and sex via self-collected biospecimens using at-home testing kits among a large and diverse cohort of men and women enrolled in the MACS/WIHS Combined Cohort Study (MWCCS) in the USA

    The study found that self-collection of dried blood spots and other samples using at-home kits was a useful and cost-effective method for screening a large cohort for sexually transmitted infections outside a clinic. This demonstrates the feasibility of decentralised, patient-centric sampling for population-level infectious disease surveillance.

    Mimiaga et al., Sexually transmitted infections (paywalled) · source ↗

    • blood
    • sti
    • dbs
    • self-collection
    • dried
    • serology
    • bd-microtainer
    • urine
  4. 2026

    An Examination of Perceptions and Usage of Dried Blood Spot Biosampling Technology for HIV Viral Load Collection Among Youth with HIV

    In a pilot mixed-methods study of youth with HIV, mailed HemaSpot-HF kits enabled home-based dried blood spot collection that participants found feasible and acceptable, supporting remote viral load monitoring and a self-management model for decentralised care.

    Gurung et al., AIDS and behavior (paywalled) · source ↗

    • blood
    • dried
    • dbs
    • self-collection
    • acceptability
    • dct
    • serology
  5. 2025

    Acceptability and Feasibility of Self-Collected Dried Blood Spot Specimens for Viral Load Monitoring among Rural Older People Living with HIV

    A study of older rural US patients found that 96 to 98 per cent of self-collected dried blood spot specimens were successfully analysed for HIV viral load, with high acceptability. However, concordance between self-reported and measured viral load was only 69 to 82 per cent, highlighting the value of objective decentralised microsampling over self-reporting.

    Walsh et al., AIDS and behavior (paywalled) · source ↗

    • dct
    • acceptability
    • blood
    • dbs
    • self-collection
    • dried
    • serology