2019 · Practical laboratory medicine · open access
Comparison of Roche Cell-Free DNA collection Tubes <sup><i>®</i></sup> to Streck Cell-Free DNA BCT <sup><i>®</i></sup> s for sample stability using healthy volunteers
Parackal et al.
The finding, in our words
Roche Cell-Free DNA Collection Tubes maintained sample integrity for up to seven days at room temperature, whereas Streck tubes preserved cfDNA stability for the full fourteen-day study period. This demonstrates that collection tube choice directly impacts sample quality during ambient shipping, a critical consideration for decentralised diagnostics.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
The homeRNA capillary blood collection and stabilization platform successfully captured lipopolysaccharide-induced inflammatory gene expression profiles. These transcriptomic responses were comparable to those obtained from traditional venous blood samples stabilized with RNAlater or PAXgene, demonstrating the platform's suitability for remote transcriptomic monitoring.
Brown et al., Analytical chemistry (paywalled) · source ↗
The True Dose TD-EPI kit demonstrated strong analytical agreement with venous blood for epirubicin monitoring, and the capillary samples remained stable for 72 hours at ambient temperature.
This developer study reports that a self-collection kit interfacing with a BD Microtainer produced RNA of sufficient quality and yield for transcriptomic analysis in a pilot group and a longitudinal rheumatology cohort. Most participants found the device easy to use, supporting its utility for decentralised blood sampling.
Eakman et al., Analytical chemistry (paywalled) · source ↗
This review summarises how emerging HPV detection methods including CRISPR/Cas systems, droplet digital PCR and isothermal amplification, combined with self-collected vaginal swabs and liquid biopsy from urine or blood, could improve screening acceptability and enable point-of-care testing compared with conventional approaches that require invasive sampling and centralised laboratory infrastructure.
Shi et al., Frontiers in cellular and infection microbiology · source ↗
Blood drawn into EDTA tubes yields robust cell-free DNA methylation profiles if plasma is prepared within 24 hours, while preservative tubes maintain profile integrity after 72-hour ambient delays, giving decentralised diagnostics a cost-effective choice for liquid biopsy collection.