2021 · International journal of STD & AIDS · paywalled
Prevalence and predictors of asymptomatic <i>Chlamydia trachomatis</i> and <i>Neisseria gonorrhoeae</i> in a Ugandan population most at risk of HIV transmission
Mabonga et al.
The finding, in our words
In Ugandan PLHIV, asymptomatic STIs were found in 3.9% overall and 5.7% in women, with risk higher under 25 years and with multiple partners. Self-sampling was highly acceptable, with over 95% finding it easy and comfortable and 83.8% believing the results, supporting decentralised STI screening using self-collected urine.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
A study of 2500 women found 99.0% agreement between first-void urine and vaginal self-sampling for HPV detection using Cobas4800, with 98.1% of participants preferring urine. Although conducted in a resource-limited setting which may limit generalisability, these results support urine as a viable sample type for decentralised, patient-centric screening.
First-void urine and self-collected vaginal swabs showed similar sensitivity and specificity to clinician-collected cervical samples for high-risk HPV detection across two real-time PCR assays, supporting their use as decentralised, patient-collected alternatives; most women preferred first-void urine for regular cervical screening.
A et al., Journal of gynecologic oncology (paywalled) · source ↗
This randomised sub-study found return rates of 10.4% for Colli-Pee, 10.1% for FLOQSwabs and 7.4% for Evalyn-Brush. All devices yielded sufficient DNA with low invalid rates, but the authors noted the study was limited by low overall participation.
Hempel et al., Archives of gynecology and obstetrics · source ↗
Community pharmacy-based testing and treatment for chlamydia and gonorrhoea using self-collected first-catch urine was highly acceptable to users and successfully identified new cases, with pharmacists efficiently prescribing antibiotic treatment. This supports decentralised sampling by showing that asymptomatic STI testing can be delivered through self-collection in non-clinical settings with good uptake and patient satisfaction.
d'Entremont-Harris et al., Journal of the American Pharmacists Association : JAPhA (paywalled) · source ↗
This pilot study demonstrated that a fully remote web-based testing programme for sexually transmitted and blood-borne infections was feasible and acceptable overall, although participants encountered specific collection challenges with the dried blood spot component.
Christensen et al., International journal of STD & AIDS · source ↗