Investigation of mycoplasma and ureaplasma species using a molecular method in male patients suffering from urethritis symptoms: a cross-sectional study in the city of Antalya

First-void urine samples showed significantly higher detection rates of HPV-specific IgG antibodies compared to midstream urine, confirming the necessity of capturing the initial stream. The study found no significant difference between 10 mL and 20 mL collection volumes, indicating flexibility in device specifications for self-collection.

The importance of first-void urine for assessing HPV-specific antibodies: A comparison with midstream urine — Van Caesbroeck et al., Human vaccines & immunotherapeutics · source ↗

• first-void
• sti
• self-collection
• serology
• hpv
• urine

The bivalent HPV vaccine showed 100 percent effectiveness against vaccine types 16 and 18 seven years post-vaccination in Thai schoolgirls, but only 32.8 percent effectiveness against other high-risk types, indicating limited cross-protection. The study used first-void urine self-collection for HPV DNA detection, demonstrating a scalable, non-invasive approach for vaccine effectiveness monitoring in decentralised settings.

Effectiveness of HPV vaccine as part of national immunization program for preventing HPV infection in Thai schoolgirls after seven years post-vaccination — Nilyanimit et al., Human vaccines & immunotherapeutics · source ↗

• first-void
• sti
• self-collection
• serology
• hpv
• urine

In a review of 91 human adenovirus-associated urethritis cases, dysuria occurred in 84% and meatitis in 34% of patients, with adenovirus type D being the most common subtype identified in first-void urine and urethral smears. Multiplex PCR screening for adenovirus in non-gonococcal urethritis can help establish accurate diagnoses and avoid unnecessary treatments.

Adenovirus-Associated Urethritis, a Not So Uncommon Entity. A Review of 91 Cases — Idigoras et al., Sexually transmitted diseases (paywalled) · source ↗

• urine
• first-void
• serology
• sti

The study found comparable seropositivity for Chlamydia trachomatis and Toxoplasma gondii among male partners of infertile couples in Odisha, with 28 per cent showing anti-Chlamydia IgA and 28 per cent anti-Toxoplasma IgM antibodies. This demonstrates that first-void urine and seminal fluid can detect relevant infections, supporting their use in decentralised fertility screening programmes.

Seropositivity of <i>Chlamydia trachomatis & Toxoplasma gondii</i> among male partners of infertile couples in Odisha, India: A facility-based exploratory study — Naik et al., The Indian journal of medical research · source ↗

• first-void
• blood
• sti
• serology
• fertility
• urine

First-void urine sampling detected Mycoplasma genitalium in 8% of 493 men with non-gonococcal urethritis at a Hong Kong STI clinic. With antimicrobial-resistance mutations in 63% of isolates, including dual-class resistance in 37%, the results support decentralised screening to guide therapy.

Emergence of antibiotic-resistant Mycoplasma genitalium as the cause of non-gonococcal urethritis in male patients at a sexually transmitted infection clinic — Lee et al., International journal of antimicrobial agents (paywalled) · source ↗

• first-void
• sti
• serology
• urine