2026 · Medicina oral, patologia oral y cirugia bucal · open access
Relationship between salivary lactoferrin level and brain amyloid load in periodontal and non-periodontal subjects
Gil-Montoya et al.
The finding, in our words
Lower salivary lactoferrin concentrations were independently associated with positive brain amyloid PET imaging and with periodontal disease, suggesting saliva lactoferrin may have value as a non-invasive biomarker in cognitive impairment assessment.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
This study used home self-collected saliva samples to successfully monitor cytokines and cortisol in mothers and infants, finding that a community singing intervention significantly reduced salivary interleukin-6 levels in mothers with postnatal depression.
Kirkpatrick et al., Brain, behavior, and immunity (paywalled) · source ↗
This review establishes that microsampling across blood, saliva, urine and stool matrices offers validated workflows and regulatory recognition for human biomonitoring comparable to conventional methods. It finds that these decentralised approaches enhance participant acceptability and enable screening in remote or low-resource settings.
In people at high risk of nasopharyngeal carcinoma, saliva showed decreased EBV load and increased EBV DNA methylation compared with controls, and a stepwise strategy that adds saliva testing to serum EBV antibodies improved triage efficiency.
Among 101 working-age women in Chicago, 70% returned at-home kits for capillary blood and saliva collection, demonstrating that patient-centric microsampling of stress biomarkers (cortisol and CRP) is feasible in diverse urban populations. This supports decentralised diagnostics for population health research.
In 104 healthy adults who collected both 24-hour urine and saliva at home, salivary iodine concentration measured at specific post-meal intervals showed excellent correlation with urinary iodine excretion. This suggests timed saliva microsampling could replace cumbersome urine collection as a reliable biomarker for assessing iodine intake in decentralised diagnostics.
Oblak et al., Radiology and oncology (paywalled) · source ↗