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OpenSampling

2024 · Nature nanotechnology · paywalled

A wearable aptamer nanobiosensor for non-invasive female hormone monitoring

Ye et al.

The finding, in our words

The wearable sensor measured oestradiol in sweat and showed a high correlation with blood levels, indicating that sweat can reflect circulating hormone changes across the menstrual cycle.

A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.

Labels

  1. 2026

    A Noninvasive Method for Dynamic Ovulation Monitoring Based on Memristor

    This study demonstrates that a memristor sensor can identify distinct electrical signatures in saliva and urine corresponding to different ovulation phases, suggesting a potential route for noninvasive home fertility monitoring.

    Chen et al., ACS omega · source ↗

    • wearable
    • multimodal
    • fertility
    • hormones
    • liquid
    • urine
    • saliva
  2. 2026

    A multimodal wearable microfluidic platform for in situ sweat cortisol monitoring with a NiHCF-enabled molecularly imprinted electrochemical sensor

    The wearable microfluidic sensor measured sweat cortisol across a range of 0.1 fM to 100 μM with a 0.043 fM detection limit. In human volunteers it tracked diurnal rhythms and stress-induced elevations from cold-pressor and exercise tests, showing agreement with ELISA, and combined with electromyography it profiled exercise fatigue by linking muscle activity to endocrine response.

    Chen et al., Biosensors & bioelectronics (paywalled) · source ↗

    • wearable
    • multimodal
    • sweat
    • cortisol
    • digital-biomarker
    • hormones
    • liquid
  3. 2022

    Wearable aptamer-field-effect transistor sensing system for noninvasive cortisol monitoring

    The authors developed a flexible aptamer-based field-effect transistor biosensor that detects nanomolar cortisol in sweat. Validated in humans during a Trier Social Stress Test, it showed correlation with salivary cortisol and enabled continuous stress monitoring via a smartwatch platform.

    Wang et al., Science advances · source ↗

    • wearable
    • multimodal
    • sweat
    • cortisol
    • hormones
    • liquid
    • saliva
  4. 2026

    Integrating Microsampling in Human Biomonitoring: Methodologies, Regulatory Frameworks, and Case Study Insights

    This review establishes that microsampling across blood, saliva, urine and stool matrices offers validated workflows and regulatory recognition for human biomonitoring comparable to conventional methods. It finds that these decentralised approaches enhance participant acceptability and enable screening in remote or low-resource settings.

    Rajamani & Poongavanam, Critical reviews in analytical chemistry (paywalled) · source ↗

    • wearable
    • acceptability
    • multimodal
    • sweat
    • blood
    • dbs
    • standards
    • dried
    • serology
    • colorectal
    • pediatric
    • stool
    • liquid
    • urine
    • validation
    • saliva
    • biomarkers
  5. 2026

    Beyond waste: menstrual blood as a powerful diagnostic tool for women's health

    Menstrual blood offers a noninvasive, patient-centric matrix for detecting endometriosis, cervical cancer, and hormonal disorders through self-collected samples. Wearable in-pad biosensors enabling real-time monitoring and long-term tracking could transform fertility evaluation and early disease detection, though standardisation and large-scale validation remain critical gaps.

    Shafiq et al., Annals of medicine and surgery · source ↗

    • wearable
    • multimodal
    • blood
    • self-collection
    • fertility
    • hormones
    • biomarkers