Using Quantitative Hormonal Fertility Monitors to Evaluate the Luteal Phase: Proof of Concept Case Study

The Mira fertility monitor's LH surge and urine E1-3G levels correlated strongly with the ClearBlue Fertility Monitor's LH surge and low-to-high shift in both postpartum and perimenopause transitions, supporting at-home urine hormone monitoring for fertility tracking.

Validating At-Home Urinary Hormone Measurements in Postpartum and Perimenopause Fertility Transitions — Bouchard et al., Women's health reports · source ↗

• urine
• self-collection
• validation
• fertility
• hormones

All five at-home urine ovulation predictor kits demonstrated high accuracy (92–97%) when compared with blood LH levels, though sensitivity varied widely from 38% to 77% with Clinical Guard the lowest. Patient experience was comparable across kits, though Clinical Guard was slightly less favoured for future use.

Similar accuracy and patient experience with different one-step ovulation predictor kits — Vanderhoff et al., Fertility and sterility (paywalled) · source ↗

• blood
• urine
• self-collection
• validation
• venous-agreement
• acceptability
• fertility
• hormones

This retrospective case series found that a protocol combining home-based urinary hormone testing with a smartphone application supported fertility management and family planning without unintended pregnancies. The findings suggest that integrating self-collected urinary data with digital tools offers a viable decentralised approach for ovulation prediction.

Helping Patients to Predict and Confirm Ovulation with the Use of Combined Urinary Hormonal and Smartphone Technology: A Proof-of-Concept Retrospective Descriptive Case Series — Leiva & Ecochard, Seminars in reproductive medicine · source ↗

• multimodal
• self-collection
• fertility
• hormones
• urine

Fertility patients commonly use direct-to-consumer ovulation prediction methods, yet reproductive endocrinologists rate the utility of these tests substantially lower than patients do. This discordance highlights the need for better patient education and guidelines to inform self-collection and interpretation of fertility biomarkers in decentralised care.

Direct-to-consumer fertility testing: utilization and perceived utility among fertility patients and reproductive endocrinologists — Peipert et al., Reproductive biomedicine online (paywalled) · source ↗

• acceptability
• self-collection
• fertility
• hormones
• urine

Daily remote urine hormone monitoring of LH and PdG, together with age and cycle start day, can identify menstrual cycle phase and day with 95% confidence; this supports precise, patient-centric cycle tracking outside clinic settings.

Using Hormone Data and Age to Pinpoint Cycle Day within the Menstrual Cycle — Hills et al., Medicina (paywalled) · source ↗

• multimodal
• rpm
• self-collection
• fertility
• hormones
• urine