2023 · J. Analytical Toxicology · paywalled
Stöth et al.
Dried urine spots with automated extraction detected over 95% of the drugs found in paired liquid urine by LC-Q-TOF.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
2026
A post-mortem case study found that Mitra microsampling devices achieved comparable qualitative toxicological detection to conventional methods across blood, urine, bile, and vitreous humour, successfully identifying methamphetamine, opioids, and alpha-PHP. Whilst limited to a single case, this shows that microsampling is a viable alternative for qualitative screening when sample volumes are restricted.
Volumetric absorptive microsampling device for forensic Toxicologic screening: A case report as proof-of-concept — Magny et al., Forensic science international (paywalled) · source ↗
2026
This review highlights that microsampling techniques such as dried blood spots and volumetric absorptive microsampling offer superior alternatives to traditional sampling for the mass spectrometry detection of prohibited substances in anti-doping analysis. It provides guidance on selecting appropriate analytical methods and sample pretreatment strategies to ensure sensitive detection and reliable storage conditions.
Mass Spectrometry-Based Anti-Doping Analysis: A Critical Review of Emerging Analytical and Sample Pretreatment Strategies — Maykar et al., Critical reviews in analytical chemistry (paywalled) · source ↗
2026
Dried blood spots and dried urine spots preserved synthetic cathinone analytes for 90 days at room temperature, with most metabolites remaining detectable throughout. This confirms dried matrix spot stability for remote toxicology applications, supporting their use in decentralised drug monitoring and screening programmes.
Characterisation of the designer cathinone N-isopropylbutylone by a multi-technique approach and its metabolic profiling and stability assessment using dried matrix spots — Odoardi et al., Analytical and bioanalytical chemistry (paywalled) · source ↗
2025
A multi-targeted procedure covered 237 prohibited substances across 11 WADA classes in dried urine spots, with environmental-stability testing for refrigeration-free transport.
LC-HRMS screening for 11 classes of prohibited substances in dried urine spots for doping control — Mazzarino et al., Analytical and Bioanalytical Chemistry (paywalled) · source ↗
2025
The authors found that a single microdose of recombinant EPO was detectable up to 72 hours using ITP and CP methods, though the Tasso microsampling device showed lower sensitivity than Mitra and Capitainer. Additionally, isotope ratio mass spectrometry successfully detected testosterone micro-dosing in all analysed samples, supported by serum testosterone levels.
Detection of a Single Microdose of Testosterone and Recombinant EPO in Healthy Volunteers — Heiland et al., Drug testing and analysis · source ↗