Remote Monitoring and Data Collection for Decentralized Clinical Trials
Daly et al.
The finding, in our words
A survey of eight biopharmaceutical companies, representing a third of the oncology market, revealed that remote monitoring adoption in oncology trials trails other therapeutic areas. Electronic diaries and digital clinical outcome assessments are the most deployed tools, while local physician network visits are least used; respondents expect adoption to rise by over 40% for most technologies within five years, with digital recruitment and local imaging prioritised for improving patient centricity.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
This review suggests that decentralised clinical trials in oncology can improve patient participation and equity but face significant regulatory, logistical and digital hurdles. It concludes that these trials offer a flexible model dependent on specific clinical contexts rather than a universal replacement for conventional methods.
Gentile et al., Critical reviews in oncology/hematology (paywalled) · source ↗
A fully remote decentralised clinical trial in Danish adults with type 2 diabetes demonstrated operational feasibility with rapid recruitment, high retention (87 percent), and excellent adherence to continuous glucose monitoring (95 percent achieving ≥70 percent data coverage) and telemedicine visits (97 percent). Activity tracker adherence was poor (12 percent) due to technical issues, but remote safety monitoring was effective with no unexpected adverse events, supporting the viability of remote diabetes management.
Viloxazine extended release improved ADHD, depression and anxiety symptoms in adults with comorbid conditions during a 14-week decentralised trial. The study demonstrates that remote monitoring via televisit, mobile app and home devices can deliver real-world efficacy and safety data for psychiatric medications.
Adler et al., The Journal of clinical psychiatry (paywalled) · source ↗
A proof-of-concept decentralised trial generated 169 support tickets over 17 months from 90% of sites, with device-related problems accounting for 46% of requests. Most issues were resolved within three days and required two to six exchanges, demonstrating that robust technical support infrastructure is essential for successful remote monitoring and wearable-based trial conduct.
Weitlaner et al., Journal of medical systems · source ↗
Hybrid decentralized oncology trials are feasible in community hospitals beyond traditional networks, reducing logistical and financial burdens and enabling rapid initiation and patient referrals within three months.