Patient perspectives on digital healthcare technology in care and clinical trials for motor neuron disease: an international survey
Helleman et al.
The finding, in our words
Most patients with motor neuron disease expressed a positive attitude towards remote monitoring and participating in decentralised clinical trials from home, with a majority finding the use of multiple digital devices acceptable for tracking respiratory function and muscle strength.
A paraphrase to the Library’s standard, never the abstract. The source is one link away and is always the authority.
A randomised trial of 47 participants using a mobile app integrated with remote patient monitoring devices achieved a 74% biomarker submission rate over four weeks, with system usability scores of 77–94 and acceptability exceeding benchmarks, showing the platform is feasible for remote data collection in decentralised clinical trials.
Dahne et al., Journal of clinical and translational science · source ↗
In a decentralised phase 1 trial, healthy adults used a clinical trial app to self-collect blood microsamples and vital signs at home, with 65 to 70 per cent successfully providing blood samples and most preferring self-collection over staff collection.
Ye et al., Contemporary clinical trials communications · source ↗
Remote smartphone cognitive testing using the ALLFTD Mobile App was feasible and acceptable for people with frontotemporal dementia and at-risk kindreds, supporting decentralised trials and improved access to research.
The study found that although participants preferred patient-centric microsampling devices for home use, the agreement with venous plasma for measuring CRP and cytokines was inconsistent, indicating that further validation is required before these methods replace standard venipuncture.
The study determined that an at-home saliva collection protocol using the passive drool method was feasible for Black women with histories of abuse, with 84% of participants completing at least one full day of adherent sampling. While the decentralised approach yielded usable cortisol data, women with histories of forced sex exposure showed lower protocol adherence scores.
Tsuyuki et al., Interactive journal of medical research (paywalled) · source ↗